ArticleScientific reports2024
A chain mediation model reveals the association between depression and cognitive function in the elderly.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Level of Depression and Associated Risk Factors Among the Elderly People Residing in Old Age Home in Bangladesh: A Cross-Sectional Study Conducted in 2025.Health science reports · 2026Article
- Statistical Methods in Aging Research: Improving Current Practices and Embracing Emerging Approaches.Annual review of statistics and its application · 2026Article
- Relationship between depression, neuropsychiatric symptoms and cognitive profiles of the elderly in India: An assessment using the ICMR-MUDRA toolbox.Global mental health (Cambridge, England) · 2026Article
- Grip strength and cognitive function of older adults through the chain mediating effect of life space mobility and depression.Scientific reports · 2025Article
- Modeling Alzheimer's disease: Bayesian copula graphical model from demographic, cognitive, and neuroimaging data.Journal of Alzheimer's disease : JAD · 2025Article
- The mediating role of instrumental activities of daily living between cognitive function and depressive symptoms in community-dwelling older adults: the Arao study.BMC psychiatry · 2025Article
- Analysis of urban-rural differences in cognitive function among empty nest older adult in China based on Blinder-Oaxaca decomposition.Frontiers in public health · 2025Article
- The relationship between marital status and cognitive function in Chinese older adults: The mediating role of depressive symptoms.Journal of Alzheimer's disease reportsArticle
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4 authors.
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Abstract
The purpose of this study was to explore the relationship between depression, cognitive function, social activities and activities of daily living ( ADL ), and verify whether social activities and ADL have a chain mediating effect between depression and cognitive function. Using the data of the fourth phase of the China Health and Retirement Longitudinal Study ( CHARLS ), 7547 elderly samples were studied. Correlation analysis and Bootstrap method were used to analyze the data to test whether social activities and ADL played a chain mediating role between depression and cognitive function in the elderly. In this study, the direct effect of depression on the cognitive function of the elderly accounted for 36.85% of the total effect. The indirect effects of social activities and ADL on depression and cognitive function of the elderly accounted for 15.99% and 44.64% of the total effects, respectively. At the same time, the chain mediating effect of social activities and ADL was significant, accounting for 2.44% of the total effect. The effect of depression on the cognitive function of the elderly is achieved through social activities, ADL and the chain mediating effect of social activities and ADL.
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