Evidence map›Paper›PMID 39732953›Full record

ArticleScientific reports2024

Enhancing early detection of Alzheimer's disease through hybrid models based on feature fusion of multi-CNN and handcrafted features.

Abdulaziz M Alayba, Ebrahim Mohammed Senan, Jalawi Sulaiman Alshudukhi

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abdulaziz M AlaybaDepartment of Information and Computer Science, College of Computer Science and Engineering, University of Ha'il, Ha'il, 81481, Saudi Arabia.
Ebrahim Mohammed SenanDepartment of Computer Science, College of Applied Sciences, Hajjah University, Hajjah, Yemen. senan1710@gmail.com.
Jalawi Sulaiman AlshudukhiDepartment of Information and Computer Science, College of Computer Science and Engineering, University of Ha'il, Ha'il, 81481, Saudi Arabia.

Funding

Deputy for Research & Innovation, Ministry of Education through Initiative of Institutional Funding at University of Ha'il - Saudi Arabia IFP-22 010
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a brain disorder that causes memory loss and behavioral and thinking problems. The symptoms of Alzheimer's are similar throughout its development stages, which makes it difficult to diagnose manually. Therefore, artificial intelligence (AI) techniques address the limitations of manual diagnosis. In this study, the images were enhanced and the active contour algorithm (ACA) was used to extract regions of interest (ROI) such as soft tissue and white matter. Strategies have been developed to diagnose AD and differentiate its stages. The first strategy is using XGBoost and ANN networks with the features of MobileNet, DenseNet, and GoogLeNet models. The second strategy is by XGBoost and ANN networks with combined features of MobileNet-DenseNet121, DenseNet121-GoogLeNet and MobileNet-GoogLeNet. The third strategy combines XGBoost and ANN networks with combined features of MobileNet-DenseNet121-Handcrafted, DenseNet121-GoogLeNet-Handcrafted, and MobileNet-GoogLeNet-Handcrafted leading to improved accuracy of the strategies and improved efficiency. XGBoost with hybrid features of DenseNet-GoogLeNet-Handcrafted achieved an AUC of 98.82%, accuracy of 98.8%, sensitivity of 98.9%, accuracy of 97.08%, and specificity of 99.5%.

Indexed as

AlgorithmsAlzheimer DiseaseEarly DiagnosisNeural Networks, ComputerHumansACAADANNCNNFusion featuresRFEXGBoost

Identifiers

PMID39732953
PMCPMC11682306

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.