Evidence map›Paper›PMID 39732883›Full record

ArticleScientific reports2024

Phytochemical composition and antidiabetic, anti-obesity, antioxidant, and cytotoxic activities of Carthamus tinctorius seed oil.

Nidal Jaradat, Mohammed Hawash, Mustafa Ghanim, Malik Alqub, Maha Rabayaa, Majdi Dwikat, Linda Issa, Fatima Hussein, Lana Asadi, Larin Yassin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nidal JaradatDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine. nidaljaradat@najah.edu.
Mohammed HawashDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Mustafa GhanimDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Malik AlqubDepartment of Allied and Applied Medical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Maha RabayaaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Majdi DwikatDepartment of Allied and Applied Medical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Linda IssaDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Fatima HusseinDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Lana AsadiDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Larin YassinDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Heba RabeeDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.
Asil GamhurDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carthamus tinctorius L. (Safflower) is widely used in traditional Japanese, Korean, Chinese, Arabian, and Persian herbal medicine to treat metabolic diseases. This study aimed to characterize C. tinctorius seed oil components and estimate its inhibitory effects on free radicals, porcine pancreatic lipase, α-amylase, and cytotoxic. To describe the phytochemical components of C. tinctorius seed oil, the Gas Chromatography-Mass Spectrometry (GC-MS) technique was performed, while reference biochemical analytical assays were utilized for biological testing. The results showed that seven fatty acids accounting for 100% of the total oil were identified, and the major fatty acid was linoleic acid (79.98 ± 0.79%), followed by oleic (11.20 ± 0.21%) and palmitic (5.71 ± 0.12%) acids. The biological tests revealed that C. tinctorius seed oil has potent inhibitory effects on free radicals, porcine pancreatic lipase, and α-amylase, with IC

Indexed as

Anti-Obesity AgentsAntioxidantsCarthamus tinctoriusHypoglycemic AgentsPhytochemicalsPlant OilsSeedsalpha-AmylasesAnimalsCell Line, TumorCell SurvivalFatty AcidsGas Chromatography-Mass SpectrometryHumansLipaseSwinealpha-AmylasesAnti-Obesity AgentsAntioxidantsFatty AcidsHypoglycemic AgentsLipasePhytochemicalsPlant OilsAntilipaseAntioxidantCarthamus tinctoriusCytotoxicitySeeds oilα-Amylase

Identifiers

PMID39732883
PMCPMC11682395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.