Evidence map›Paper›PMID 39732699›Full record

ArticleDiagnostic pathology2024

(1, 3)-beta-D-Glucan in bronchoalveolar lavage fluid: a useful biomarker in diagnosis of invasive pulmonary infection caused by Hormographiella aspergillata?

Haiyan Ye, Jinhui He, Jing Huang, Patrick Chu, Junru Liu, Rosana Wing-Shan Poon, Fanfan Xing, Simon Kam-Fai Lo, Ricky Wing-Tong Lau, Jasper Fuk-Woo Chan and 2 more

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In one paragraph

Article in Diagnostic pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Haiyan YeDepartment of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Jinhui HeDepartment of Hematology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Jing HuangDepartment of Hematology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Patrick ChuDepartment of Hematology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Junru LiuDepartment of Pathology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Rosana Wing-Shan PoonDepartment of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China.
Fanfan XingDepartment of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Simon Kam-Fai LoDepartment of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Ricky Wing-Tong LauDepartment of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Jasper Fuk-Woo ChanDepartment of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Susanna Kar-Pui LauState Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Kelvin Hei-Yeung ChiuDepartment of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China. hychiu09@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hormographiella aspergillata is a rare hyaline mold causing invasive fungal infection in humans, until the frequent use of antifungal prophylaxis in immunocompromised hosts. Due to the high mortality of H. aspergillata infection, early recognition and treatment are crucial. Previous case reports suggested that serum (1,3)-beta-D-Glucan (BG) is one of the diagnostic aids for H. aspergillata infection. Here we report for the first time a case of pulmonary H. aspergillata infection with a negative serum BG but positive bronchoalveolar lavage fluid (BAL) BG. This may suggest that BAL BG is a useful and additional microbiological marker for prompt identification of this fatal invasive fungal infection (IFI). But it should be interpreted together with the clinical presentation, imaging, and other laboratory results.

Indexed as

beta-GlucansBiomarkersBronchoalveolar Lavage FluidInvasive Fungal InfectionsAgaricalesAntifungal AgentsFatal OutcomeHumansLung Diseases, FungalPredictive Value of TestsProteoglycansAntifungal Agentsbeta-GlucansBiomarkerspolysaccharide-KProteoglycans(1,3)-beta-D-GlucanAmphotericin BHormographiella aspergillataInvasive fungal infection

Identifiers

PMID39732699
PMCPMC11681749

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