Evidence map›Paper›PMID 39732688›Full record

ArticleCancer cell international2024

Ultrasound-responsive nanoparticles for nitric oxide release to inhibit the growth of breast cancer.

Haiyan Yang, Guangrong Zheng, GuoChen Li, Jincui Chen, Licui Qi, Yong Luo, Tengfei Ke, Jie Xiong, Xiaojuan Ji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer cell international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haiyan Yang *Department of Ultrasound, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.
Guangrong Zheng *Department of Radiology, Yan'an Hospital, Affiliated to Kunming Medical University, Yan'an Hospital of Kunming City, Kunming, 650051, China.
GuoChen Li *Department of Radiology, Yan'an Hospital, Affiliated to Kunming Medical University, Yan'an Hospital of Kunming City, Kunming, 650051, China.
Jincui ChenDepartment of Ultrasound, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.
Licui QiDepartment of Ultrasound, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.
Yong LuoDepartment of Ultrasound, The People's Hospital of Chongqing Liang Jiang New Area, Chongqing, 400010, China.
Tengfei KeDepartment of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan Campus), Kunming, 650118, China. ketengfei@kmmu.edu.cn.
Jie XiongInstitute of Ultrasound Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. xj306654@hospital.cqmu.cn.
Xiaojuan JiDepartment of Ultrasound, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China. 400146@cqmu.edu.cn.

Funding

Chongqing Medical Youth Top-notch Talent YXQN202446Chongqing Postdoctoral Science Foundation 2023CQBSHTB1005Chongqing Postdoctoral Science Foundation CSTB2023NSCQ-BHX0035Chongqing women and Children General Project Fund 2020FY108Graduate Innovation Foundation of Kunming Medical University 2024B013Graduate Innovation Foundation of Kunming Medical University 2024S122the Natural Science Foundation of Chongqing CSTB2024NSCQ-MSX0102
6 · The paper itself

Abstract

Gas therapy represents a promising strategy for cancer treatment, with nitric oxide (NO) therapy showing particular potential in tumor therapy. However, ensuring sufficient production of NO remains a significant challenge. Leveraging ultrasound-responsive nanoparticles to promote the release of NO is an emerging way to solve this challenge. In this study, we successfully constructed ultrasound-responsive nanoparticles, which consisted of poly (D, L-lactide-co-glycolic acid) (PLGA) nanoparticles, natural L-arginine (LA), and superparamagnetic iron oxide nanoparticles (SPIO, Fe

Indexed as

Breast cancerGas therapyNitric oxideUltrasound

Identifiers

PMID39732688
PMCPMC11681665

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.