Evidence map›Paper›PMID 39732656›Full record

Observational studyBMC pregnancy and childbirth2024

Risk factors for constipation during pregnancy: a multicentre prospective cohort study.

Zivile Sabonyte-Balsaitiene, Tomas Poskus, Eugenijus Jasiunas, Diana Ramasauskaite, Diana Buzinskiene, Grazina Drasutiene, Agne Okuleviciute, Jolita Zakareviciene

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zivile Sabonyte-BalsaitieneClinic of Obstetrics and Gynaecology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University , 03101 Santariskiu Str. 2, LT-08661, Vilnius, Lithuania. zivile.sabonyte-balsaitiene@mf.vu.lt.ORCID http://orcid.org/0000-0001-5570-9306
Tomas PoskusTranslational Health Research, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Eugenijus JasiunasTranslational Health Research, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Diana RamasauskaiteClinic of Obstetrics and Gynaecology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University , 03101 Santariskiu Str. 2, LT-08661, Vilnius, Lithuania.
Diana BuzinskieneClinic of Obstetrics and Gynaecology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University , 03101 Santariskiu Str. 2, LT-08661, Vilnius, Lithuania.
Grazina DrasutieneClinic of Obstetrics and Gynaecology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University , 03101 Santariskiu Str. 2, LT-08661, Vilnius, Lithuania.
Agne OkuleviciuteFaculty of Medicine, Vilnius University, 03101, Vilnius, Lithuania.
Jolita ZakarevicieneClinic of Obstetrics and Gynaecology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University , 03101 Santariskiu Str. 2, LT-08661, Vilnius, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConstipation is frequently encountered in the population of pregnant women. Physical activity and nutritional factors are considered common causes of constipation; however, their impact on this population has not yet been evaluated precisely. This study aimed to assess the prevalence of constipation and its risk factors during pregnancy and postpartum.

methodsA prospective observational cohort study was conducted in 3 hospitals in Lithuania, including women with early viable pregnancies using questionnaires on demographic, obstetric, nutrition, behaviour, peri-anal disease, and birth data. All women with an early viable pregnancy (<12 weeks' gestation) aged 18 - 45 years who gave written informed consent were included. The Rome III criteria defined constipation. Independent risk factors were identified using multivariate analysis.

resultsIn all, 263 (55.9%) women developed constipation. Multivariate analysis identified haemorrhoidal disease during pregnancy (OR 8.25, 95% CI 4.41-15.4, p < 0.001), inadequate physical activity (OR 1.66, 95% CI 1.03-2.69, p=0.038), not participating in sports (OR 1.98, 95% CI 1.24-3.17, p=0.004), and monthly income 300-500 euros (OR 1.97, 95% CI 1.22-3.19, p=0.006) as significant predictors of constipation during pregnancy. Lower education was defined as a protective factor (retrospectively, secondary education by 2.2 times (OR 0.45, 95% CI 0.22-0.89, p=0.022) and unfinished secondary - by 1.84 times (OR 0.20, 95% CI 0.05-0.90, p=0.036) reduced the possibility of constipation development).

conclusionsIn conclusion, haemorrhoidal disease during pregnancy, low physical activity, and low monthly income are independent risk factors for constipation during pregnancy. Lower education significantly reduces the incidence of this condition.

Indexed as

ConstipationPregnancy ComplicationsAdolescentAdultExerciseFemaleHemorrhoidsHumansIncomeLithuaniaMiddle AgedMultivariate AnalysisPostpartum PeriodPregnancyPrevalenceProspective StudiesConstipationPregnancyRisk factors

Identifiers

PMID39732656
PMCPMC11682611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.