Evidence map›Paper›PMID 39732274›Full record

ArticleExperimental neurology2025

Unique infrared thermographic profiles and altered hypothalamic neurochemistry associated with mortality in endotoxic shock.

Sean N Curtis, Catherine A Mayer, Tracey L Bonfield, Thomas M Raffay, Juliann M DiFiore, Richard J Martin, Adriana C Hoffman, Michael A Folz, Ryan W Bavis, Mathias Dutschmann and 1 more

Abstract read
In one paragraph

Article in Experimental neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sean N CurtisDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Catherine A MayerDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Tracey L BonfieldDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, United States of America.
Thomas M RaffayDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Juliann M DiFioreDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Richard J MartinDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Adriana C HoffmanDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Michael A FolzSchool of Engineering, Case Western Reserve University, Cleveland, OH, United States of America.
Ryan W BavisDepartment of Biology, Bates College, Lewiston, ME, United States of America.
Mathias DutschmannPulmonary, Critical, and Sleep Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Peter M MacFarlaneDepartment of Pediatrics, UH Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America. Electronic address: pmm71@case.edu.

Funding

Central & Peripheral Mechanisms of Respiratory & Autonomic Control Dysfunction in a Novel Model of SIDS: Predictive Biomarkers and the Role of the Extracellular MatrixR01HD111415 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI Peter MacFarlane · 2024 to 2026
$1.7M
NICHD NIH HHS R01 HD111415
6 · The paper itself

Abstract

Neonatal sepsis results in significant morbidity and mortality, but early detection is clinically challenging. In a neonatal rat model of endotoxic shock, we characterised unique infrared thermographic (IRT) profiles in skin temperature that could identify risk of later mortality. Ten-day old rats were placed in a thermally stable isolette and IRT images of cranial (T

Indexed as

HypothalamusShock, SepticThermographyAnimalsAnimals, NewbornFemaleInfrared RaysLipopolysaccharidesMaleRatsRats, Sprague-DawleySkin TemperatureLipopolysaccharidesEndotoxic shockHypothalamusMicrogliaNeonatesThermal imaging

Identifiers

PMID39732274
PMCPMC12918751

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.