Evidence map›Paper›PMID 39732220›Full record

ArticleNeuroImage2025

RegBoost: Enhancing mouse brain image registration using geometric priors and Laplacian interpolation.

Atchuth Naveen Chilaparasetti, Andy Thai, Pan Gao, Xiangmin Xu, M Gopi

Abstract read
In one paragraph

Article in NeuroImage, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atchuth Naveen ChilaparasettiDepartment of Computer Science, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: achilapa@uci.edu.
Andy ThaiDepartment of Computer Science, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: andy.thai@uci.edu.
Pan GaoDepartment of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: gaop2@uci.edu.
Xiangmin XuDepartment of Computer Science, University of California, Irvine, Irvine, CA 92617, USA; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: xiangmix@hs.uci.edu.
M GopiDepartment of Computer Science, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: gopi@ics.uci.edu.

Funding

Cell-type-specific neural circuit connectomes in the mouse models of aging and Alzheimer's diseaseU01AG076791 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kim Green, ERAN A MUKAMEL · 2022 to 2026
$13.6M
NIA NIH HHS U01 AG076791
6 · The paper itself

Abstract

We show in this work that incorporating geometric features and geometry processing algorithms for mouse brain image registration broadens the applicability of registration algorithms and improves the registration accuracy of existing methods. We introduce the preprocessing and postprocessing steps in our proposed framework as RegBoost. We develop a method to align the axis of 3D image stacks by detecting the central planes that pass symmetrically through the image volumes. We then find geometric contours by defining external and internal structures to facilitate image correspondences. We establish Dirichlet boundary conditions at these correspondences and find the displacement map throughout the volume using Laplacian interpolation. We discuss the challenges in our standalone framework and demonstrate how our new approaches can improve the results of existing image registration methods. We expect our new approach and algorithms will have critical applications in brain mapping projects.

Indexed as

AlgorithmsBrainBrain MappingImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingAnimalsMiceGeometry processingLaplacianMouse brainNeuroimagingRegistration

Identifiers

PMID39732220
PMCPMC12066957

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.