Evidence map›Paper›PMID 39731711›Full record

ArticleJournal of food science2025

Synthesis and characterization of turmeric extract-β-cyclodextrin inclusion complexes: Metabolite profiling and antioxidant activity.

Chagam Koteswara Reddy, Choong Hwan Lee

Abstract read
In one paragraph

Article in Journal of food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chagam Koteswara ReddyDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-5160-0079
Choong Hwan LeeDepartment of Bioscience and Biotechnology, Konkuk University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Turmeric (Curcuma longa L.) has gained significant attention for its medicinal properties, yet its therapeutic applications are often limited by low aqueous solubility and susceptibility to environmental factors. This study investigates the formulation of a curcumin-rich turmeric extract-β-cyclodextrin inclusion complex (TUE-β-CD) to enhance its bioactivity and stability. Structural characterization and metabolite profiling of the inclusion complex were conducted using field-emission scanning electron microscopy, thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and ultrahigh-performance liquid chromatography coupled with LTQ-Orbitrap-mass spectrometry (UHPLC-LTQ-Orbitrap-MS). Results revealed that the inclusion complexes exhibit distinct morphological, spectroscopic, crystalline, and thermal properties compared to both curcumin-rich TUE and β-CD, confirming successful encapsulation of turmeric metabolites within β-cyclodextrin cavities. Results of UHPLC-LTQ-Orbitrap-MS confirmed that β-CD had differential encapsulation efficiencies for bioactive compounds of turmeric. The results suggest that the inclusion complex significantly improves the thermal stability and bioactivity of turmeric extract, thereby enhancing its potential applications as a functional component in both food and non-food industries.

Indexed as

Antioxidantsbeta-CyclodextrinsCurcumaPlant ExtractsChromatography, High Pressure LiquidCurcuminMass SpectrometrySolubilitySpectroscopy, Fourier Transform InfraredThermogravimetryX-Ray DiffractionAntioxidantsbeta-CyclodextrinsCurcuminPlant Extractsturmeric extractCurcuma longainclusion complexmetabolite profileUHPLC–LTQ–Orbitrap–MSβ‐cyclodextrin

Identifiers

PMID39731711
PMCPMC11976684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.