Evidence map›Paper›PMID 39731693›Full record

ReviewJournal of echocardiography2025

Diagnostic and prognostic potential of left atrial strain in cardiovascular disease: a narrative review.

Sana Tantawi, Elio Issa, Kamal Matli, Raymond Farah, Christy Costanian, Steven Miner, Shafika Assaad, Georges Ghanem

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of echocardiography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sana Tantawi *Faculty of Medical Sciences, Lebanese University, Hadath, Beirut, Lebanon.
Elio Issa *Gilbert and Rose‑Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Kamal MatliService de Cardiologie, Centre Hospitalier de Haguenau, Haguenau, France.
Raymond FarahNeuroscience Research Center (NRC), Lebanese University, Beirut, Lebanon.
Christy CostanianSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. chc02@yorku.ca.ORCID http://orcid.org/0000-0003-4395-7278
Steven MinerDivision of Cardiology, Southlake Regional Health Centre, Newmarket, ON, Canada.
Shafika AssaadSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon.
Georges GhanemDepartment of Cardiology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left atrial strain (LAS) was recently introduced as a parameter that reflects on left atrial function. Consequently, changes in LAS can inform the development of cardiovascular diseases, hence providing a window for non-invasive and cost-effective testing of these diseases and their complications at early stages of development, potentially offering a segway towards preventive interventions. LAS has yet to be implemented into standard practice. Therefore, we aimed to synthesize the current evidence on the diagnostic and prognostic potentials of LAS in a variety of cardiovascular diseases. We attempted to elucidate sufficient evidence to support uptake into clinical practice. A systematic search of four databases (Medline, PubMed, Embase, CINAHL) was performed for articles published within the last 5 years, for inclusion in this narrative review. A total of 3921 articles were identified, among which only 43 articles were included. LAS showed diagnostic potential in detecting (1) paroxysmal atrial fibrillation in stroke patients, (2) left atrial appendage dysfunction in patients with nonvalvular atrial fibrillation and heart failure with reduced ejection fraction, and finally (3) diastolic dysfunction in patients with arrhythmias, valvulopathies, acute coronary syndrome, primary arterial hypertension, and heart failure. LAS was also prognostic for the development of (1) atrial fibrillation in hypertensive patients, cardiovascular events in patients with (2) valvular diseases and (3) ischemic heart diseases, and (4) heart failure in patients with and without diastolic dysfunction. This review highlights the potential of LAS in identifying certain cardiac pathologies and their repercussions on patient prognosis, which should prompt courageous integration into the clinical workup while emphasizing areas for future research to guarantee successful and safe implementation into clinical practice.

Indexed as

Atrial Function, LeftCardiovascular DiseasesEchocardiographyHeart AtriaAtrial FibrillationHumansPrognosisLeft atrial functionLeft atrial strainPrognosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.