ArticleJournal of medical ultrasonics (2001)2025
Impact of adipocytes on ultrasound evaluation of parathyroid adenomas.
Article in Journal of medical ultrasonics (2001), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Clinical Impact of Rare Subtypes of Parathyroid Adenoma: A Systematic Review.Journal of personalized medicine · 2026Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeParathyroid lipoadenomas are difficult to recognize preoperatively; hence, they may remain undetected. Difficulty in recognition is thought to be due to the adipocytes present in the tumor. This study aimed to clarify the impact of adipocytes as a component of parathyroid adenomas on ultrasound evaluation.
methodsEighteen parathyroid adenoma cases, in which the adipose tissue accounted for more than 10% of the tumors, were included in this study. Of these, five were consistent with lipoadenomas. Twenty-five consecutive patients with parathyroid adenoma without adipocytes were used as controls.
resultsUltrasonography revealed a lipoadenoma detection rate of 20.0%. This increased to 80.0% at re-examinations performed after obtaining information from other imaging modalities. Compared with parathyroid adenoma cases with no adipocytes or few adipocytes, the frequencies of ill-defined margins, iso- and/or hyperechogenicity, heterogeneous consistency with a two-tone pattern, poor vascular flow, no polar artery, and no hyperechoic line were significantly higher in parathyroid lipoadenoma cases. The hyperechoic and isoechoic areas in tumors with a two-tone pattern correspond to adipocyte- and parathyroid cell-rich areas, respectively. The lipoadenoma tumor sizes measured using ultrasound tended to be smaller than the actual sizes.
conclusionsThe characteristic ultrasound findings of lipoadenomas were clearly different from those of parathyroid adenomas with or without adipocytes. We believe that our findings may contribute to an increased detection rate of lipoadenomas and allow us to consider them in the differential diagnosis.
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