Evidence map›Paper›PMID 39731504›Full record

ArticleClinical transplantation2024

Outcomes of Acute Kidney Injury After Pediatric Liver Transplantation: A 1-Year Follow-Up.

Jiemei Ji, Shengfeng Liang, Jian Lai, Zhongxuan Mao, Yunan Lin, Yuyan Lan, Jingchen Liu

Abstract read
PubMed Full text at PMC Publisher
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Article in Clinical transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiemei JiDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.ORCID https://orcid.org/0000-0002-6730-5701
Shengfeng LiangDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jian LaiDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Zhongxuan MaoDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yunan LinDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Yuyan LanDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jingchen LiuDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative acute kidney injury (AKI) and chronic kidney disease (CKD) following pediatric liver transplantation (PLT) have not been comprehensively studied. This study aimed to evaluate the correlation between AKI and both 1-year CKD and mortality.

methodsThis retrospective study included 132 children aged between 3 months and 12 years who underwent PLT between 2017 and 2021. Postoperative AKI and CKD after 1 year were assessed according to KDIGO criteria. AKI was classified as mild, moderate, or severe based on severity as well as transient (≤2 days) and persistent (>2 days) based on duration. CKD occurrence was the primary outcome, whereas all-cause mortality was the secondary outcome.

resultsAKI developed in 45.4% of children, with 40.7% mild, 37.1% moderate, and 22.2% severe. Half of the children with AKI subsequently developed CKD within 1 year, compared to 23.1% without AKI. Multivariate analysis indicated that moderate AKI, severe AKI, and persistent AKI were risk factors for CKD development (moderate AKI, OR = 3.8, 95% CI = 1.2-12.3; severe AKI, OR = 7.4, 95% CI = 1.4-38.3; persistent AKI, OR = 9.7, 95% CI = 2.3-36.4). The overall mortality rate within 1 year after surgery was 9.8%. Children with severe AKI and AKI lasting longer than 2 days exhibited a higher mortality rate than those without AKI.

conclusionsThe development of postoperative AKI is relatively common after PLT, and the severity and duration of AKI are associated with CKD and mortality within 1 year.

Indexed as

Acute Kidney InjuryLiver TransplantationPostoperative ComplicationsChildChild, PreschoolFemaleFollow-Up StudiesGlomerular Filtration RateGraft SurvivalHumansInfantMalePrognosisRenal Insufficiency, ChronicRetrospective StudiesRisk Factorsacute kidney injurychronic kidney diseasepediatric liver transplantation

Identifiers

PMID39731504
PMCPMC11681610

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