ArticleJournal of cosmetic dermatology2025
Preparation and Evaluation of the Effectiveness of an Anti-Wrinkle Cream Containing Equisetum arvense and Soybean Extracts.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
Funding
Abstract
backgroundSkin aging is a multifaceted condition marked by the development of wrinkles, reduced suppleness, and uneven pigmentation. Both endogenous and exogenous factors contribute to skin aging. Studies have examined the possible anti-aging advantages of horsetail and soybean extracts, which are abundant in antioxidants.
methodsA study was conducted to develop and assess the stability of an anti-wrinkle cream combining horsetail and soybean extracts over a period of 6 months. This study was a pilot study that was prospective and noncomparative in nature. An investigation was performed to explore the efficiency of a treatment on wrinkles on the forehead. The study involved 15 volunteers between the ages of 35 and 55, and the modified Fitzpatrick wrinkle grading scale (FWS) method was used to assess the results. The participants were directed to administer cream to the forehead region for a duration of eight sequential weeks. Images were acquired at the initial stage and after 8 weeks of treatment. An independent investigator evaluated the improvement in the overall appearance of the forehead skin by comparing clinical images taken before and after the therapy.
resultsThe cream exhibited exceptional stability, showing no noteworthy alterations in pH, viscosity, or microbiological count. The clinical findings demonstrated a notable decrease in the average FWS score from 8.7 ± 1.3 to 6.1 ± 1.8 (p < 0.005) after the treatment. 93.4% of the individuals experienced a positive alteration in the appearance of their forehead wrinkles.
conclusionThe formulated cream presents a hopeful method to tackle skin aging issues, backed by its durability and effectiveness in diminishing wrinkles. Additional investigation is necessary to clarify the underlying mechanisms.
trial registrationIRCT20190917044799N1.
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