Evidence map›Paper›PMID 39731098›Full record

Trial reportPediatric rheumatology online journal2024

Assessing the impact of the iPeer2Peer program for adolescents with juvenile idiopathic arthritis: a mixed-methods randomized controlled trial.

Fareha Nishat, Lauren Kelenc, Roberta Berard, Ciaran Duffy, Brian Feldman, Paula Forgeron, Adam M Huber, Nadia Luca, Heinrike Schmeling, Lynn Spiegel and 11 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatric rheumatology online journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03116763 (The iPeer2Peer Program for Adolescents With Juvenile Idiopathic Arthritis), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03116763 nacompletednot on this map

The iPeer2Peer Program for Adolescents With Juvenile Idiopathic Arthritis: A Randomized Controlled Trial

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2017 to 2023Enrolled164ConditionsJuvenile Idiopathic ArthritisArmsiPeer2Peer Mentorship, Active Comparator: Control Group
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Fareha NishatChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Lauren KelencChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Roberta BerardDivision of Rheumatology, Children's Hospital, London Health Sciences Centre, London, ON, Canada.
Ciaran DuffyChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Brian FeldmanChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Paula ForgeronSchool of Nursing, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada.
Adam M HuberDivision of Pediatric Rheumatology, IWK Health Centre, Halifax, NS, Canada.
Nadia LucaDivision of Rheumatology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Heinrike SchmelingAlberta Children's Hospital, Calgary, AB, Canada.
Lynn SpiegelDepartment of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada.
Lori TuckerDivision of Rheumatology, British Columbia Children's Hospital, Vancouver, BC, Canada.
Karen Watanabe-DuffyChildren's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Tieghan KillackeyChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Chitra LallooChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Brittany WilesChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Anya NairChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Sofia OlaizolaChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Brenna McDermottChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Farideh TavangarLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada.
Sara Ahola KohutDivision of Gastroenterology Hepatology and Nutrition, The Hospital for Sick Children, Toronto, ON, Canada.
Jennifer N StinsonChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada. jennifer.stinson@sickkids.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundJuvenile Idiopathic Arthritis (JIA) is a chronic pediatric illness, whereby youth experience physical, emotional and psychosocial challenges that result in reduced health related quality of life (HRQL). Peer mentoring has been shown to improve disease self-management in adults with chronic conditions, with mixed results in younger populations. Building on our pilot work - which supported the feasibility and initial effectiveness of the iPeer2Peer program - the objective of this study was to assess the clinical effectiveness of the program in youth with JIA through a waitlist randomized controlled trial.

methodsEighty-one youth (aged 12-18) were randomized to the intervention group and matched with trained peer mentors (18-25 years; successfully managing their JIA), completing of up to ten 30-min video calls over a 15-week period. Eighty-three youth in the control group received standard care. Outcome assessments occurred at enrollment, 15 weeks post randomization and 6-months post randomization. The primary outcome was self-management, measured using the TRANSITION-Q. Secondary outcomes were HRQL, pain, emotional distress, disease knowledge, self-efficacy, and perceived social support. These were assessed using linear mixed effects models. Content analysis of semi-structured interviews and focus groups was used to assess satisfaction with the program with mentors and mentees upon study completion.

resultsIn total, 164 youth (mean age 14.4 ± 1.9 years, 78% female) were randomized to the study. The proposed sample size was not reached due to challenges in recruitment, likely impacted by the COVID-19 pandemic. The iPeer2Peer program did not show significant improvement in self-management (p = 0.7), or any of the secondary outcomes. Three key categories emerged from content analysis: (1) Fulfillment and Support Through Shared Experience, (2) Enhancing Program Delivery and (3) Strategies to Boost Engagement. These findings highlight that mentees valued the ability to converse with mentors who empathized with their disease experience, while mentors found it fulfilling to support mentees, and noted that they could have benefited from this type of support themselves.

conclusionWhile the iPeer2Peer did not result insignificant changes in clinical outcomes, both mentors and mentees were satisfied with the program and felt that mentorship provided real-world benefits for disease management and overall wellbeing.

trial registrationClinicalTrials.gov, NCT03116763. Registered 31, March 2017, https://www. CLINICALTRIALS: gov/study/NCT03116763.

Indexed as

Arthritis, JuvenilePeer GroupQuality of LifeAdolescentAdultChildCOVID-19FemaleHumansMaleMentoringMentorsSelf EfficacySelf-ManagementSocial SupportYoung AdultAdolescentJuvenile idiopathic arthritisOnlinePeer supportRandomized control trialSelf-management

Identifiers

PMID39731098
PMCPMC11674074

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.