Evidence map›Paper›PMID 39731085›Full record

ArticleMicrobial cell factories2024

The role of lignin in 17β-estradiol biodegradation: insights from cellular characteristics and lipidomics.

Hanyu Pan, Peng Hao, Qiannan Li, Zongshuo Lv, Kun Gao, Xiaojun Liang, Lianyu Yang, Yunhang Gao

Abstract read
In one paragraph

Article in Microbial cell factories, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Catabolic Mechanism of 17β-Estradiol inJournal of microbiology and biotechnology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanyu PanCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China.
Peng HaoCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China.
Qiannan LiCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China.
Zongshuo LvCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China.
Kun GaoCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China.
Xiaojun LiangInstitute of Animal Husbandry, Ningxia Academy of Agriculture and Forestry, Yinchuan, 750002, China.
Lianyu YangCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China. yangly@jlau.edu.cn.
Yunhang GaoCollege of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, China. gaoyunhang@163.com.

Funding

China Agriculture Research System of MOF and MARA CARS-37Jilin Province Science and Technology Development Plan-Key Consulting Project of Chinese Academy of Engineering JL2023-07National Key Research and Development Program Projects 2022YFD1601203National Key Research and Development Program Projects 2022YFD1602501Ningxia Hui Autonomous Region Agricultural Science and Technology Independent Innovation Project NGSB-2021-12
6 · The paper itself

Abstract

17β-estradiol (E2) is an endocrine disruptor, and even trace concentrations (ng/L) of environmental estrogen can interfere with the endocrine system of organisms. Lignin holds promise in enhancing the microbial degradation E2. However, the mechanisms by which lignin facilitates this process remain unclear, which is crucial for understanding complex environmental biodegradation in nature. In this study, we conducted a comprehensive analysis using cellular and lipidomics approaches to investigate the relationship between E2-degrading strain, Rhodococcus sp. RCBS9, and lignin. Our findings demonstrate that lignin significantly enhances E2 degradation efficiency, reaching 94.28% within 5 days with the addition of 0.25 mM lignin. This enhancement is associated with increased microbial growth and activity, reduced of membrane damages, and alleviation of oxidative stress. Fourier Transform Infrared Spectroscopy (FTIR) results indicate that lignin addition alters lipid peaks. Consequently, by analyzing lipid metabolism changes, we further elucidate how lignin addition promotes E2 degradation.

Indexed as

Biodegradation, EnvironmentalEstradiolLigninLipidomicsRhodococcusEndocrine DisruptorsLipid MetabolismOxidative StressSpectroscopy, Fourier Transform InfraredEndocrine DisruptorsEstradiolLignin17β-estradiolBiodegradationCells characteristicsLigninLipidomicsMechanisms of lipid action

Identifiers

PMID39731085
PMCPMC11673921

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.