Evidence map›Paper›PMID 39730577›Full record

ArticleScientific reports2024

Assessment of systemic steroid use and its determinants among admitted patients at Debre Berhan University Hakim Gizawu Teaching Hospital.

Abate Wondesen Tsige, Kalkidan Simegn, Dessale Abate Beyene, Kassahun Dires Ayenew, Yehualashet Teshome Wondmkun, Bedilu Linger Endalifer, Abyou Seyfu Ambaye, Samuel Berihun Dagnew, Siraye Genzeb Ayele

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abate Wondesen TsigeDepartment of Pharmacy, Clinical Pharmacy Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, P.O. Box 445, Debre Berhan, Ethiopia. Abatewondesen@dbu.edu.et.
Kalkidan SimegnDepartment of Pharmacy, Clinical Pharmacy Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, P.O. Box 445, Debre Berhan, Ethiopia.
Dessale Abate BeyeneDepartment of Pharmacy, Clinical Pharmacy Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, P.O. Box 445, Debre Berhan, Ethiopia.
Kassahun Dires AyenewDepartment of Pharmacy, Pharmacology and Toxicology Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, Debre Berhan, Ethiopia.
Yehualashet Teshome WondmkunDepartment of Pharmacy, Pharmaceutical Analysis Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, Debre Berhan, Ethiopia.
Bedilu Linger EndaliferDepartment of Pharmacy, Clinical Pharmacy Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, P.O. Box 445, Debre Berhan, Ethiopia.
Abyou Seyfu AmbayeDepartment of Pharmacy, Social and Administrative Pharmacy Unit, Asrat Weldeyes Health Sciences Campus, Debre Berhan University, Debre Berhan, Ethiopia.
Samuel Berihun DagnewDepartment of Pharmacy, Clinical Pharmacy Unit, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Siraye Genzeb AyeleDepartment of Midwifery, School of Nursing and Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rational use of steroids is essential in the long term for improving patient safety. Systemic steroids are important in clinical treatment, but if they are misused, they might have negative effects. This study assessed systemic steroid use and its determinants at Debre Berhan University Hakim Gizawu Teaching Hospital (DBUHGTH), Ethiopia. A cross-sectional study was conducted among 210 admitted patients at the Medical ward of DBUHGTH. A simple random sampling method was used to recruit study participants. The data was collected from patient medical records and patient interviews using a structured data abstraction and patient interview format. Binary logistic regression was employed to identify the potential predictors of systemic steroid use. Finally, the results were interpreted and presented by tables, charts, and graphs. Most study participants were 142 (67.62%) male. The mean age of the participants was 44.94 (SD, 19.2) years. Prednisolone was mostly utilized drug 130 (42.07%), followed by hydrocortisone 81 (26.21%), beclomethasone 58 (18.77%), and dexamethasone 40 (12.94%). Respiratory disorders 112 (53.34%), meningitis 25 (11.91%), and rheumatoid arthritis 19 (9.05%) were the top three disease conditions in which steroids were used with the highest frequency. Most systemic steroids were administered orally, 130 (42.07%). Short-acting (hydrocortisone, beclomethasone) 139 (44.98%) were mostly used, followed by intermediate-acting steroids (prednisolone) 130 (42.07%). Study participants in the 18-40 age range were approximately 2.5 times more likely than those in the 65 + age group to be using systemic steroids (AOR = 2.5, 95% CI 2.86-6.07). Prednisolone was mostly utilized, followed by hydrocortisone, beclometasone, and dexamethasone drugs in the medical ward of DBUHGTH.

Indexed as

Hospitals, TeachingPrednisoloneSteroidsAdolescentAdultAgedBeclomethasoneCross-Sectional StudiesDexamethasoneEthiopiaFemaleGlucocorticoidsHumansHydrocortisoneMaleMiddle AgedBeclomethasoneDexamethasoneGlucocorticoidsHydrocortisonePrednisoloneSteroidsAdultEthiopiaHospitalSteroidsSystemic steroids

Identifiers

PMID39730577
PMCPMC11681244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.