ArticleScientific reports2024
Impact of race and ethnicity on glaucoma progression detection by perimetry and optical coherence tomography.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Artificial Intelligence-Guided Endpoint Selection for Neuroprotection Trials in Glaucoma.American journal of ophthalmology · 2026Article
- Retinal nerve fiber layer thickness profile in an Iranian adult population.Scientific reports · 2025Article
Corrections and comments
- Update of
Authors and funding
6 authors.
Funding
Abstract
This study assessed the impact of race and ethnicity on longitudinal test variability and time to detect glaucoma progression using standard automated perimetry (SAP) and optical coherence tomography (OCT). The sample consisted of 47,003 SAP tests from 5402 eyes and 25,480 OCT tests from 4125 eyes, with 20% of participants self-identifying as Black or African American and 80% as White; 29% as Hispanic or Latino and 71% as Not Hispanic or Latino. Variability was measured using standard deviations of residuals from linear regression models for SAP mean deviation (MD) and OCT retinal nerve fiber layer (RNFL) thickness over time. Results showed significantly greater SAP variability in Black or African American (1.80 ± 1.30 dB) compared to White participants (1.56 ± 1.21 dB; P < 0.001) and in Hispanic or Latino (1.81 ± 1.46 dB) compared to Not Hispanic or Latino individuals (1.52 ± 1.10 dB; P < 0.001). OCT variability was higher in Black or African American (2.3 ± 1.5 μm) compared to White (2.1 ± 1.3 μm; P < 0.001) and in Not Hispanic or Latino (2.2 ± 1.3 μm) compared to Hispanic or Latino (2.1 ± 1.2 μm; P = 0.029). Increased SAP variability delayed progression detection, while OCT showed minimal differences. These findings suggest that higher perimetric variability in Black or African American and Hispanic or Latino may affect glaucoma progression detection using SAP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.