Trial reportJournal of substance use and addiction treatment2025
Text message-delivered cannabis use disorder treatment with young adults: A large randomized clinical trial.
Trial report in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Rural and Urban Variation in Mobile Health Substance Use Disorder Treatment Mechanisms and Efficacy.Rural mental health · 2026Article
- Daily web survey data collection of time-varying cannabis use motives and contexts, with implications for adaptive interventions: A pilot study.Drug and alcohol dependence · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundTwo scientific and clinical challenges for treating cannabis use disorder (CUD) are developing efficacious treatments with high likelihood of uptake and scalability, and testing the clinical mechanisms by which treatments work. Because young adults experience more CUD than other age groups, a need exists to test the efficacy and hypothesized causal pathways of novel treatments for CUD. Text-delivered treatments have the potential to reach young adults by increasing access and perceived privacy.
methodsWe conducted a randomized clinical trial (n = 1078) of a 4-week CUD treatment with U.S. young adults from Colorado and Tennessee. Participants were allocated to Peer Network Counseling-text (PNC-txt), a text-message delivered brief motivational interviewing informed treatment, or a wait-list control condition, and followed for 6 months.
resultsNo significant direct treatment effects on cannabis use were found between experimental conditions. However, significant treatment effects were identified on hypothesized mediators: readiness to change and protective behavioral strategies. Tests of indirect effects using latent change score mediation modeling showed the treatment group (PNC-txt) increased in readiness to change and protective behavioral strategies at the 1-month follow-up period, which led to decreases in the number of days participants used cannabis from baseline to 6-months, compared to controls.
conclusionsWhile no direct treatment effects were identified, PNC-txt appears successful in reducing cannabis use relative to controls indirectly by activating participants' motivation to change and through teaching harm reduction strategies. Results suggest targeting readiness to change and protective behavioral strategies as modifiable clinical mechanisms when treating CUD in young adults.
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