ArticleAmerican journal of otolaryngology
Proximity to traffic is associated with worse symptom severity in patients with chronic rhinosinusitis with nasal polyps.
Article in American journal of otolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000-2018).World journal of otorhinolaryngology - head and neck surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundEnvironmental exposures may be associated with increased severity of chronic rhinosinusitis (CRS). However, research examining associations of traffic related air pollution with CRS is limited. The purpose of this study was to determine the association between residential traffic proximity and CRS with nasal polyposis (CRSwNP) severity in an existing database of adults in the United States.
methodsThis study was conducted on data gathered from 181 participants documented in the NAVIGATE I and NAVIGATE II randomized control trials within the OPTINOSE database. Zip codes for the testing locations of each participant were recorded and EPA traffic proximity data was extracted for each location. Traffic proximity was defined as the average annual daily traffic at major roads within the zip code. SNOT-22 scores were assessed as a measure of CRSwNP severity. The association between traffic proximity and SNOT-22 scores were determined using multiple linear regression.
resultsThere were 81 female and 100 male participants. The majority of participants were White not Hispanic (84.5 %). On adjusted regression, there was a weak but significant direct association of increased traffic proximity with SNOT-22 scores (β: 0.003; 95 % CI: 0.0003, 0.006; p = 0.03).
conclusionsIncreasing traffic proximity, suggestive of exposure to higher levels of pollution, was significantly associated with increased severity of CRSwNP. These findings suggest that pollutant exposure should be considered in CRS assessment and management. Future prospective studies on the association of traffic related air pollution and how pollutants affect symptom severity, may help to better elucidate the role the environment has in CRS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.