Evidence map›Paper›PMID 39729154›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2025

[Leading symptom: motor manifestations with impaired consciousnes : Management of epileptic seizures and status epilepticus].

Leona Möller, Clara Jünemann, Christian Claudi, Patrick Schramm

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leona MöllerKlinik für Neurologie, Standort Marburg, Universitätsklinikum Gießen und Marburg, Marburg, Deutschland.
Clara JünemannKlinik für Neurologie, Standort Marburg, Universitätsklinikum Gießen und Marburg, Marburg, Deutschland.
Christian ClaudiNeurologische Klinik, Standort Gießen, Universitätsklinikum Gießen und Marburg, Klinikstraße 33, 35392, Gießen, Deutschland.
Patrick SchrammNeurologische Klinik, Standort Gießen, Universitätsklinikum Gießen und Marburg, Klinikstraße 33, 35392, Gießen, Deutschland. patrick.schramm@neuro.med.uni-giessen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epileptic seizures, which are often accompanied by a reduction in vigilance, are a common emergency. Every first-time epileptic seizure should be investigated further. Particular attention should be paid to whether it is an acute symptomatic seizure, which is an acute event characterized by a metabolic disorder or acute cerebral damage within a certain period of time, or possibly epilepsy. In terms of differential diagnosis, psychogenic nonepileptic seizures also pose a challenge, as they are often not easy to distinguish from epileptic seizures, but require a different therapeutic approach. Persistent epileptic seizures in the sense of status epilepticus (duration: > 5 min) are also common in the (pre)clinical emergency situation and require immediate initiation of adequate therapy, which consists of rapid and sufficient administration of benzodiazepines. Nasal administration is a quick and simple option here, particularly in the prehospital setting. Furthermore, persistent reductions in vigilance are a not infrequently occurring phenomenon in the (pre)clinical setting, which is, however, based on numerous differential diagnoses. Here, nonconvulsive status epilepticus should be considered as a possible cause and rapid diagnosis using EEG should be sought in order to begin early treatment, which improves patient outcomes.

Indexed as

EpilepsyStatus EpilepticusAnticonvulsantsBenzodiazepinesDiagnosis, DifferentialElectroencephalographyEmergenciesHumansAnticonvulsantsBenzodiazepinesAcute symptomatic seizuresBenzodiazepinesConvulsive syncopeDisorder of consciousnessPsychogenic nonepileptic seizures

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.