Evidence map›Paper›PMID 39729141›Full record

SynthesisNeurosurgical review2024

In the era of transition from fiction to reality: Robotic-assisted neurointervention-a systematic review and meta-analysis.

Ahmet Günkan, Marcio Yuri Ferreira, Jhon E Bocanegra-Becerra, Umur Anil Pehlivan, Marina Vilardo, Gabriel Semione, Sávio Batista, Christian Ferreira, Yafell Serulle, Ismail Yardimcioglu and 3 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Design and Performance of a Neurosurgery Assisting Device.Biomimetics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ahmet GünkanDepartment of Radiology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey. gunkanahmet@gmail.com.ORCID http://orcid.org/0000-0002-6236-5633
Marcio Yuri FerreiraDepartment of Neurosurgery, Lenox Hill Hospital, New York, NY, US.
Jhon E Bocanegra-BecerraAcademic Department of Surgery, School of Medicine, Cayetano Heredia Peruvian University, Lima, Peru.
Umur Anil PehlivanDepartment of Radiology, Baskent University Adana Dr. Turgut Noyan Application and Research Center, Adana, Turkey.
Marina VilardoSchool of Medicine, Catholic University of Brasilia, DF, Brazil, Brasilia.
Gabriel SemioneFaculty of Medicine, University of West Santa Catarina, Joaçaba, Santa Catarina, Brazil.
Sávio BatistaFaculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Christian FerreiraDepartment of Neurosurgery, Lenox Hill Hospital, New York, NY, US.
Yafell SerulleDepartment of Neurosurgery, Lenox Hill Hospital, New York, NY, US.
Ismail YardimciogluDepartment of Radiology, Bridgeport Hospital, Bridgeport, CT, US.
Raphael BertaniDepartment of Neurosurgery, University of São Paulo, São Paulo, SP, Brazil.
Gabriele CiccioCHU Saint-Étienne Clinical and Exercise Physiology, Department of Radiology, Saint-Etienne, France.
Pascal JabbourNeurological Surgery, Thomas Jefferson University, Philadelphia, PA, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn recent years, the application of robotic assistance in diagnostic and therapeutic endovascular neurointerventional procedures has gained notable attention. In this systematic review and meta-analysis, we aim to evaluate the feasibility, safety, and current indications of robotic-assisted neurointerventions and to assess the degree of robotic assistance and reasons for unplanned manual conversion from robotic assistance.

methodsWe searched Medline, Scopus, Web of Science, and Cochrane Library databases following PRISMA guidelines and included studies with ≥ 4 patients reporting on robotic-assisted neurointerventions. We analyzed outcomes including technical success, manual conversion, procedure-related complications, morbidity, and mortality with a random-effects meta-analysis. We also identified causes of manual conversion and conducted subanalyses by procedure type and robotic system.

resultsThirteen studies, comprising 538 robotic-assisted neurointerventions, were included. Procedures were primarily diagnostic cerebral angiograms (n = 348), cerebral aneurysm embolizations (n = 127), and carotid artery stenting (n = 37). The CorPath GRX (Corindus) robotic system was employed in the majority of cases (n = 355). Across all studies, the technical success rate was 93%, and the procedure-related complication rate was 0.7%. Manual steps were necessary in all cases due to inherent procedural requirements. Unplanned manual conversion from robotic assistance was necessary in 7% of cases. Further analysis of failures identified challenging anatomies, loss of working length, and mechanical failures as the most common reasons.

conclusionsThis systematic review and meta-analysis found that, with a certain degree of manual assistance, robotic-assisted neurointervention is highly feasible, safe, and capable of performing DCA, CAS, and therapeutic neurointerventions that can be executed with a single microcatheter involving simple coiling, stent-assisted coiling, and flow diverter embolization. However, unplanned manual conversion is not uncommon. Improvements in working length and mechanical parts, including the cassette robotic arm and console, as well as CorPath GRX compatibility with 0.035-inch wires, may reduce the rates of manual conversion for current indications. Nonetheless, technical adaptations are essential to broaden the scope of therapeutic neurointervention indications.

Indexed as

Endovascular ProceduresHumansNeurosurgical ProceduresRoboticsRobotic Surgical ProceduresEndovascular roboticsNeurointerventionRemote neurointerventionRobotRobotic-assistedRobotic surgical procedure

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.