Evidence map›Paper›PMID 39729099›Full record

SynthesisAbdominal radiology (New York)2025

Magnetic resonance imaging features of uterine adenosarcoma: case series and systematic review.

Kazuhiko Morikawa, Akira Baba, Satoshi Matsushima, Yohei Ohki, Megumi Shiraishi, Ayako Kawabata, Natsuko Ukai, Hiroya Ojiri

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kazuhiko MorikawaDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan. k.morikawa@jikei.ac.jp.
Akira BabaDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Satoshi MatsushimaDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Yohei OhkiDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Megumi ShiraishiDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Ayako KawabataDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Natsuko UkaiDepartment of Diagnostic Pathology, The Jikei University School of Medicine, Tokyo, Japan.
Hiroya OjiriDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo comprehensively summarize the characteristics of magnetic resonance imaging (MRI) findings of uterine adenosarcoma through a systematic review and case series analysis.

methodsA literature search was conducted in MEDLINE, Scopus, and Embase databases on June 3, 2024. In total, 25 cases from 23 articles were selected, and five cases from the authors' institution were included. Two board-certified radiologists evaluated the demographic, clinical, and radiological data.

resultsThe median age at diagnosis was 48.5 years (range: 9-79 years). The most frequent chief complaint was abnormal bleeding (96.7%), pathological T1 stage was predominant (85.2%), and 55.2% of the patients had sarcomatous overgrowth. Locoregional/distant recurrence occurred in 36.4% of the patients. MRI findings revealed that the mean longest lesion size was 9.3 cm. However, most lesions were located in the uterine body (93.1%) and primarily involved the endometrium (96.6%). Most cases (90.0%) were polypoid lesions with 80.8% protruding into the cervical canal. Cystic changes were prevalent (96.5%) and hemorrhage was observed in 84.6% of the evaluated cases. Lesions showed high (51.7%) or intermediate (48.3%) signal intensity compared with the uterine myometrium on T2-weighted imaging. Furthermore, all lesions showed heterogeneous enhancement on contrast-enhanced MRI, and the mean apparent diffusion coefficient value was 1.05 × 10

conclusionOur findings provide a comprehensive analysis of MRI features in uterine adenosarcoma cases, highlighting key characteristics that may aid in preoperative diagnosis and differentiation from other uterine malignancies.

Indexed as

AdenosarcomaMagnetic Resonance ImagingUterine NeoplasmsAdolescentAdultAgedChildFemaleHumansMiddle AgedUterusMagnetic resonance imagingMalignancies tumorMRISystematic reviewUterine adenosarcoma

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.