Evidence map›Paper›PMID 39728972›Full record

ArticleVeterinary sciences2024

Intestinal Osteosarcoma with Liver Metastasis in a Dog with a History of Recurrent Cotton-Based Toy Fragment Ingestion.

Andrada Negoescu, Claudiu Gal, Andrei Mihaila, Constantin Mihaila, Cornel Cătoi, Marian Taulescu

Abstract readCase Reports
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Focus on Tumours in Pet Animals.Veterinary sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrada NegoescuDepartment of Anatomic Pathology, Faculty of Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Claudiu GalDepartment of Veterinary Pathology, Synevovet, 81 Pache Protopopescu, 021408 Bucharest, Romania.ORCID 0000-0003-0000-9737
Andrei MihailaAndivet Hospital, 330004 Deva, Romania.
Constantin MihailaAndivet Hospital, 330004 Deva, Romania.
Cornel CătoiDepartment of Anatomic Pathology, Faculty of Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Marian TaulescuDepartment of Anatomic Pathology, Faculty of Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-8987-6038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine extraskeletal osteosarcomas are mesenchymal, osteoid producing tumors that can arise in soft tissues without initial involvement of the bones. An 8-year-old intact male Beagle dog presented with anorexia, abdominal pain, intermittent vomiting and melena. The patient had a history of recurrent ingestion of cotton based-toy fragments, but no prior surgical procedures involving the abdominal cavity. During the exploratory laparotomy, a mass was identified in the jejunal wall. Surgical resection was performed, and tissue samples were collected for pathological examination. Histologically, the mass was diagnosed as osteoblastic osteosarcoma with fragments of cotton fiber material. The neoplastic cells were immunolabeled for vimentin and BMP-2, further supporting the morphological diagnosis. Seven months after the surgery, metastatic nodules were identified in the liver. The dog died ten months after intestinal mass resection. This case represents the first documented instance of metastatic intestinal osteosarcoma potentially caused by ingestion of cotton fiber material.

Indexed as

cotton fibersdogextraskeletal osteosarcomaimmunohistochemistryintestine

Identifiers

PMID39728972
PMCPMC11680206

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.