Evidence map›Paper›PMID 39728941›Full record

ArticleVeterinary sciences2024

Exploring Gene Expression and Alternative Splicing in Duck Embryonic Myoblasts via Full-Length Transcriptome Sequencing.

Jintao Wu, Shuibing Liu, Dongcheng Jiang, Ya'nan Zhou, Hongxia Jiang, Xiaoyun Xiao, Boqian Zha, Yukai Fang, Jie Huang, Xiaolong Hu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jintao WuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.ORCID 0009-0008-6818-4025
Shuibing LiuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Dongcheng JiangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Ya'nan ZhouCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Hongxia JiangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Xiaoyun XiaoCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Boqian ZhaCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Yukai FangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Jie HuangCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Xiaolong HuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Huirong MaoCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Sanfeng LiuCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
Biao ChenCollege of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.ORCID 0000-0003-1852-5289

Funding

National Natural Science Foundation of China 32102541Natural Science Foundation of Jiangxi Province 20212BAB215016Technology System of Modern Agricultural Poultry Industry of Jiangxi Province JXARS-09
6 · The paper itself

Abstract

The duck industry is vital for supplying high-quality protein, making research into the development of duck skeletal muscle critical for improving meat and egg production. In this study, we leveraged Oxford Nanopore Technologies (ONT) sequencing to perform full-length transcriptome sequencing of myoblasts harvested from the leg muscles of duck embryos at embryonic day 13 (E13), specifically examining both the proliferative (GM) and differentiation (DM) phases. Our analysis identified a total of 5797 novel transcripts along with 2332 long non-coding RNAs (lncRNAs), revealing substantial changes in gene expression linked to muscle development. We detected 3653 differentially expressed genes and 2246 instances of alternative splicing, with key genes involved in essential pathways, such as ECM-receptor interaction and Notch signaling, prominently featured. Additionally, we constructed a protein-protein interaction network that highlighted critical regulators-

Indexed as

differentially expressed genesduckfull-length transcriptomeskeletal muscle

Identifiers

PMID39728941
PMCPMC11680404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.