Evidence map›Paper›PMID 39728799›Full record

ArticleToxins2024

Assessment of the Effects of Anatoxin-a In Vitro: Cytotoxicity and Uptake.

Cristina Plata-Calzado, Ana I Prieto, Ana M Cameán, Angeles Jos

Abstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristina Plata-CalzadoArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González 2, 41012 Seville, Spain.ORCID 0000-0001-5465-8084
Ana I PrietoArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González 2, 41012 Seville, Spain.ORCID 0000-0002-5157-4763
Ana M CameánArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González 2, 41012 Seville, Spain.ORCID 0000-0003-1524-748X
Angeles JosArea of Toxicology, Faculty of Pharmacy, Universidad de Sevilla, Profesor García González 2, 41012 Seville, Spain.ORCID 0000-0001-7546-3294

Funding

Consejería de Transformación Económica, Industria, Conocimiento y Universidades de la Junta de Andalucía PREDOC_00447MICIU/AEI /10.13039/501100011033 PID2023-147444OB-I00MICIU/AEI/10.13039/501100011033 PID2019-104890RB-I00
6 · The paper itself

Abstract

Anatoxin-a (ATX-a) is a cyanotoxin whose toxicological profile has been underinvestigated in comparison to other cyanotoxins such as microcystins (MCs) or cylindrospermopsin (CYN). However, its wide distribution, occurrence, and toxic episodes justify more attention. It is classified as a neurotoxin, but it has also been reported to affect other organs and systems. Thus, the aim of this study was to establish, as a first tier in its toxicological evaluation, its cytotoxicity in a wide range of cell lines representative of potential target organs (N2a, SH-SY5Y, HepG2, Caco2, L5178Y Tk

Indexed as

Cell SurvivalCyanobacteria ToxinsTropanesAnimalsCell LineHumansTandem Mass Spectrometryanatoxin aCyanobacteria ToxinsTropanesanatoxin-acytotoxicitygene expressionin vitrorisk assessmentuptake

Identifiers

PMID39728799
PMCPMC11680428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.