The Langmuir Monolayer as a Model Membrane System for Studying the Interactions of Poly(Butyl Cyanoacrylate) Nanoparticles with Phospholipids at the Air/Water Interface.

Georgi Yordanov, Ivan Minkov, Konstantin Balashev

Abstract read

In one paragraph

Article in Membranes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Interfacial Interactions of Nanoparticles and Molecular Nanostructures with Model Membrane Systems: Mechanisms, Methods, and Applications.Membranes · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Georgi YordanovDepartment of Inorganic Chemistry, Faculty of Chemistry and Pharmacy, Sofia University St. Kliment Ohridski, 1 "James Bourchier" Blvd., 1164 Sofia, Bulgaria.

Ivan MinkovDepartment of Chemistry, Biochemistry, Physiology, and Pathophysiology, Faculty of Medicine, Sofia University, 1407 Sofia, Bulgaria.ORCID 0000-0001-9373-9127

Konstantin BalashevDepartment of Physical Chemistry, Faculty of Chemistry and Pharmacy, Sofia University St. Kliment Ohridski, 1 "James Bourchier" Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0002-5272-9974

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(butyl cyanoacrylate) (PBCA) nanoparticles have numerous applications, including drug and gene delivery, molecular imaging, and cancer therapy. To uncover the molecular mechanisms underlying their interactions with cell membranes, we utilized a Langmuir monolayer as a model membrane system. This approach enabled us to investigate the processes of penetration and reorganization of PBCA nanoparticles when deposited in a phospholipid monolayer subphase. Atomic force microscopy (AFM) was employed to visualize Langmuir-Blodgett (LB) films of these nanoparticles. Additionally, we examined the state of a monolayer of Pluronic F68, a stabilizer of PBCA nanoparticles in suspension, by measuring the changes in relative surface area and surface potential over time in the barostatic regime following PBCA suspension spreading. Based on these findings, we propose a molecular mechanism for nanoparticle reorganization at the air-water interface.

Indexed as

atomic force microscopy (AFM)Langmuir monolayersPluronic 68poly(butyl cyanoacrylate) nanoparticles

Identifiers

PMID39728704

DOI10.3390/membranes14120254

PMCPMC11678612

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.