Evidence map›Paper›PMID 39728553›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Pleozymes: Pleiotropic Oxidized Carbon Nanozymes Enhance Cellular Metabolic Flexibility.

Anh T T Vo, Karthik Mouli, Anton V Liopo, Philip Lorenzi, Lin Tan, Bo Wei, Sara A Martinez, Emily A McHugh, James M Tour, Uffaf Khan and 2 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anh T T VoCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.ORCID 0000-0001-8400-0291
Karthik MouliCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.ORCID 0000-0002-1671-5727
Anton V LiopoCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.ORCID 0000-0003-4218-2159
Philip LorenziMetabolomics Core Facility, Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0003-0385-7774
Lin TanMetabolomics Core Facility, Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Bo WeiMetabolomics Core Facility, Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sara A MartinezMetabolomics Core Facility, Department of Bioinformatics & Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Emily A McHughDepartment of Chemistry, Rice University, Houston, TX 77005, USA.
James M TourDepartment of Chemistry, Rice University, Houston, TX 77005, USA.
Uffaf KhanCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.
Paul J DerryCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.
Thomas A KentCenter for Genomics and Precision Medicine, Institute of Bioscience and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.ORCID 0000-0002-9877-7584

Funding

Novel Carbon Nanozyme Mechanisms for Traumatic Brain InjuryR01NS094535 · NINDS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HEGDE, MURALIDHAR L, KENT, THOMAS · 2015 to 2024
$4.1M
NIH HHS R01NS094535NINDS NIH HHS R01 NS094535Welch Foundation BE-0048
6 · The paper itself

Abstract

Our group has synthesized a pleiotropic synthetic nanozyme redox mediator we term a "pleozyme" that displays multiple enzymatic characteristics, including acting as a superoxide dismutase mimetic, oxidizing NADH to NAD

Indexed as

fatty acid oxidationmitochondrial metabolismNADHnanozymeoxidized activated carbon nanoparticlesredox mediator

Identifiers

PMID39728553
PMCPMC11728746

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.