Evidence map›Paper›PMID 39728515›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Electrochemical Method for the Design of New Possible Gadolinium-Based Contrast Agents.

Claudia Carbone, Aaron Stoeckle, Manuel Minardi, Fulvio Uggeri, Luciano Lattuada, Alessandro Minguzzi, Alberto Vertova

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Claudia CarboneLaboratory of Applied Electrochemistry, Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi, 19, 20133 Milan, Italy.ORCID 0000-0002-1865-6820
Aaron StoeckleInstitute of Physical Chemistry and Electrochemistry, Leibniz University Hanover, Callinstr. 3A, 30167 Hanover, Germany.
Manuel MinardiLaboratory of Applied Electrochemistry, Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi, 19, 20133 Milan, Italy.
Fulvio UggeriBracco Imaging SpA, via Egidio Folli 50, 20134 Milano, Italy.
Luciano LattuadaBracco Imaging SpA, via Egidio Folli 50, 20134 Milano, Italy.ORCID 0000-0001-6577-2595
Alessandro MinguzziLaboratory of Applied Electrochemistry, Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi, 19, 20133 Milan, Italy.ORCID 0000-0002-8130-4465
Alberto VertovaLaboratory of Applied Electrochemistry, Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi, 19, 20133 Milan, Italy.ORCID 0000-0003-3858-9730

Funding

Bracco (Italy) NA
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) is a technique that employs strong magnetic fields and radio frequencies to generate detailed images of the body's interior. In oncology patients, gadolinium-based contrast agents (GBCAs) are frequently administered to enhance the visualization of tumors. Those contrast agents are gadolinium chelates, characterized by high stability that prevents the release of the toxic gadolinium ion into the body. This work is part of the research for alternative nanoscaled GBCAs. Following the synthesis and characterization of zinc hexacyanoferrate nanoparticles, gadolinium ions were successfully incorporated into a hexacyanoferrate-based matrix, deposited on FTO-coated glass used as working electrode in a gadolinium salt solution, by applying a fixed potential determined through cyclic voltammetry studies. The presence of gadolinium inside the matrix was confirmed by EDX.

Indexed as

gadolinium-based contrast agentsgadolinium ionZnHCF nanoparticles

Identifiers

PMID39728515
PMCPMC11679725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.