Evidence map›Paper›PMID 39728423›Full record

ReviewMedical sciences (Basel, Switzerland)2024

An Unusual Case of Nephrotic Range Proteinuria in a Short-Standing Type 1 Diabetic Patient with Newly Diagnosed Systemic Lupus Erythematosus: A Case Report and Literature Review.

Marco Dominguez Davalos, José C De La Flor, Carlos Bedia Castillo, Roxana Lipa Chancolla, Celia Rodríguez Tudero, Jacqueline Apaza, Rocío Zamora, Michael Cieza-Terrones

Abstract readCase ReportsReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco Dominguez DavalosDepartment of Nephrology, Hospital Cayetano Heredia, Lima 15002, Peru.
José C De La FlorDepartment of Nephrology, Hospital Central Defense Gomez Ulla, 280467 Madrid, Spain.ORCID 0000-0001-9346-2279
Carlos Bedia CastilloFaculty of Medicine, Peruana Cayetano Heredia University, Lima 15002, Peru.ORCID 0009-0008-5098-944X
Roxana Lipa ChancollaAnatomic Pathology Department, Instituto Nacional de Salud del Niño, Lima 15082, Peru.
Celia Rodríguez TuderoDepartment of Nephrology, Hospital Universitario de Salamanca, 37007 Salamanca, Spain.
Jacqueline ApazaDepartment of Nephrology, Hospital Rey Juan Carlos, 28933 Madrid, Spain.
Rocío ZamoraDepartment of Nephrology, Hospital Universitario General Villalba, 28400 Madrid, Spain.ORCID 0009-0008-8130-8248
Michael Cieza-TerronesDepartment of Nephrology, Hospital Cayetano Heredia, Lima 15002, Peru.ORCID 0000-0002-6558-7231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLupus podocytopathy (LP) is a non-immune complex-mediated glomerular lesion in systemic lupus erythematosus (SLE), characterized by the diffuse effacement of podocyte processes without immune complex deposition or with only mesangial immune complex deposition. LP is a rare cause of nephrotic syndrome in SLE patients with implications for prognosis and treatment. CASE REPORT: We present the case of a 28-year-old woman with a medical history of type 1 diabetes mellitus (T1DM) who presented with lower limb edema, dyspnea, hypercholesterolemia, with nephrotic range proteinuria, without acute kidney injury, and laboratory findings compatible with auto-immune hemolytic anemia. They had negative infectious serology, positive antinuclear antibody (ANA), and an eye fundus examination showing diabetic retinopathy. A biopsy was performed to define the etiology of the renal involvement, which was compatible with LP. Following immuno-suppressive and antiproteinuric therapy, the patient evolved with the complete remission of the nephrotic syndrome.

conclusionsLupus podocytopathy is an infrequent anatomopathological entity, so this case is presented as the first reported in Peru, and a literature review is made.

Indexed as

Diabetes Mellitus, Type 1Lupus Erythematosus, SystemicProteinuriaAdultFemaleHumansNephrotic SyndromePodocyteslupus podocytopathynephrotic syndromesystemic lupus erythematosus

Identifiers

PMID39728423
PMCPMC11677153

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.