Evidence map›Paper›PMID 39728175›Full record

ArticleJournal of functional biomaterials2024

Effects of Platelet-Rich Fibrin on Bone Healing Around Implants Placed in Maxillary Sinuses: A Histomorphometric Assessment in Rabbits.

Gustavo Augusto Grossi-Oliveira, Eduardo Dallazen, Thabet Asbi, João Matheus Fonseca-Santos, Paulo Domingos Ribeiro-Júnior, Jamil A Shibli, Cinthya Massari Grecco, Osvaldo Magro-Filho, Carlos Fernando Mourão, Doron Haim and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gustavo Augusto Grossi-OliveiraDepartment of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.
Eduardo DallazenDepartment of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.ORCID 0000-0002-7994-5634
Thabet AsbiMaccabi-Dent Research Department, Tel-Aviv 6801298, Israel.ORCID 0000-0002-1875-7402
João Matheus Fonseca-SantosDepartment of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.
Paulo Domingos Ribeiro-JúniorDivision of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, UNISAGRADO, Bauru 17011-160, SP, Brazil.
Jamil A ShibliDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.ORCID 0000-0003-1971-0195
Cinthya Massari GreccoDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, SP, Brazil.
Osvaldo Magro-FilhoDepartment of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.
Carlos Fernando MourãoDepartment of Basic and Clinical Translational Sciences, School of Dental Medicine, Tufts University, Boston, MA 02111, USA.ORCID 0000-0001-5775-0222
Doron HaimMaccabi-Dent Research Department, Tel-Aviv 6801298, Israel.
Yaniv MayerDepartment of Periodontology, Rambam Health Care Campus, Haifa 3525408, Israel.ORCID 0000-0001-5500-7961
Leonardo P FaveraniDepartment of Oral Diagnosis, Division of Oral and Maxillofacial Surgery, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba 13414-903, SP, Brazil.ORCID 0000-0003-2249-3048

Funding

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq, Brazil) 314479/2023-6
6 · The paper itself

Abstract

This study investigated the effect of platelet-rich fibrin (PRF) on bone healing around implants placed in elevated sinus cavities. Forty New Zealand albino rabbits were divided into eight groups, based on the time of sacrifice (14 or 40 days) and the material used: blood clot (control), hydroxyapatite (HA) from bovine bone, HA combined with PRF, and PRF alone. Each group consisted of five animals (n = 5). A histological analysis measured bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO). The results showed significant increases in the BIC and BAFO values at 40 days compared to 14 days in most groups. At day 14, the HA+PRF group had higher BIC than the clot and the PRF alone groups. At 40 days, HA+PRF maintained the highest BIC across all groups (

Indexed as

alveolar bone lossbone substitutesdental implantsplatelet-rich fibrin

Identifiers

PMID39728175
PMCPMC11677102

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.