Evidence map›Paper›PMID 39728137›Full record

ArticleMarine drugs2024

Optimization of Collagen Extraction from Fish Scales Using Tris-Glycine Buffer: A Taguchi Methodological Approach.

Mokgadi Ursula Makgobole, Stanley Chibuzor Onwubu, Abayomi Baruwa, Nomakhosi Mpofana, Zodidi Obiechefu, Deneshree Naidoo, Andile Khathi, Blessing Mkhwanazi

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In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mokgadi Ursula MakgoboleSchool of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.
Stanley Chibuzor OnwubuDepartment of Chemistry, Faculty of Applied Sciences, Durban University of Technology, Durban 4001, South Africa.ORCID 0000-0002-4499-1534
Abayomi BaruwaDepartment of Biotechnology and Food Science, Durban University of Technology, Durban 4001, South Africa.
Nomakhosi MpofanaDepartment of Somatology, Faculty of Health Sciences, Durban University of Technology, Durban 4001, South Africa.
Zodidi ObiechefuDepartment of Chemistry, Faculty of Applied Sciences, Durban University of Technology, Durban 4001, South Africa.ORCID 0000-0002-7863-7103
Deneshree NaidooDepartment of Chemistry, Faculty of Applied Sciences, Durban University of Technology, Durban 4001, South Africa.
Andile KhathiSchool of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.ORCID 0000-0002-2246-0038
Blessing MkhwanaziDiscipline of Dietetics and Nutrition, College of Agriculture, University of KwaZulu-Natal, Durban 3201, South Africa.ORCID 0000-0003-1181-3587

Funding

National Research Foundation BAAP22060920380
6 · The paper itself

Abstract

Collagen, a critical biomaterial with wide applications in pharmaceuticals, cosmetics, and medical industries, can be sourced sustainably from fish scales. This study optimizes the extraction of collagen using Tris-Glycine buffer from fish scales via the Taguchi method. Various extraction parameters-buffer concentration, temperature, pH, and time-were evaluated to identify optimal conditions. Under optimal conditions (0.5 M of acetic acids, volume of acids of 100 mL, soaking time of 120 min, and Tris-Glycine buffer of 10 mL), the results demonstrate that temperature and buffer concentration significantly influence collagen yield, with a collagen purity of 17.14 ± 0.05 mg/g.

Indexed as

Animal ScalesCollagenFishesGlycineAnimalsBuffersCollagen Type IHydrogen-Ion ConcentrationTemperatureTromethamineBuffersCollagenCollagen Type IGlycineTromethaminecollagen extractionfish scalesoptimizationsustainable biomaterialsTaguchi methodTris-Glycine bufferyield

Identifiers

PMID39728137
PMCPMC11677649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.