Evidence map›Paper›PMID 39727974›Full record

ReviewCurrent issues in molecular biology2024

Updates on the Activity, Efficacy and Emerging Mechanisms of Resistance to Cefiderocol.

Gabriele Bianco, Matteo Boattini, Monica Cricca, Lucia Diella, Milo Gatti, Luca Rossi, Michele Bartoletti, Vittorio Sambri, Caterina Signoretto, Rossella Fonnesu and 2 more

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  7. Review
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  12. Review
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  15. Review
  16. Spontaneous Emergence of Cefiderocol Resistance inAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gabriele BiancoDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-8180-5075
Matteo BoattiniDepartment of Public Health and Paediatrics, University of Torino, 10124 Turin, Italy.ORCID 0000-0001-6726-2716
Monica CriccaDepartment of Medical and Surgical Sciences-DIMEC, Alma Mater Studiorum, Section Microbiology, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2815-3119
Lucia DiellaDepartment of Biomedical Sciences, Humanitas University, 20089 Milan, Italy.
Milo GattiDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, Section Pharmacology, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-3018-3779
Luca RossiDepartment of Diagnostics and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.
Michele BartolettiDepartment of Biomedical Sciences, Humanitas University, 20089 Milan, Italy.
Vittorio SambriDepartment of Medical and Surgical Sciences-DIMEC, Alma Mater Studiorum, Section Microbiology, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-5012-7355
Caterina SignorettoDepartment of Diagnostics and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.
Rossella FonnesuMicrobiology and Virology Unit, Azienda Ospedaliera Universitaria Integrata Di Verona, 37134 Verona, Italy.ORCID 0009-0007-1916-6878
Sara CominiOperative Unit of Clinical Pathology, Carlo Urbani Hospital, 60035 Jesi, Italy.
Paolo GaibaniDepartment of Diagnostics and Public Health, Microbiology Section, Verona University, 37134 Verona, Italy.ORCID 0000-0003-3791-8635

Funding

University of Verona FUR2024
6 · The paper itself

Abstract

In recent years, novel antimicrobials have been developed to counter the emergence of antimicrobial resistance and provide effective therapeutic options against multidrug-resistant (MDR) Gram-negative bacilli (GNB). Cefiderocol, a siderophore cephalosporin, represents a novel valuable antimicrobial drug for the treatment of infections caused by MDR-GNB. The mechanism of cefiderocol to penetrate through the outer membrane of bacterial cells, termed "

Indexed as

antimicrobialscefiderocolemerging resistanceGram-negativein vitro activitymultidrug resistance

Identifiers

PMID39727974
PMCPMC11674395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.