Evidence map›Paper›PMID 39727961›Full record

ArticleCurrent issues in molecular biology2024

Skin Microbiota, Circulating Metabolic Biomarker, Epilepsy: A Mendelian Randomization Analysis.

Yongheng Wang, Tianyi Liu, Shangying Wu, Jiawei Sun, Mingdao Mu, Zhiyuan Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yongheng WangSchool of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou 310018, China.
Tianyi LiuSchool of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou 310018, China.
Shangying WuSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong 999077, China.
Jiawei SunSchool of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou 310018, China.
Mingdao MuSchool of Medicine, Southeast University, Nanjing 210009, China.
Zhiyuan YangSchool of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou 310018, China.

Funding

National Natural Science Foundation of China 82201705Natural Science Foundation of Jiangsu Province BK2022040821
6 · The paper itself

Abstract

Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures. Currently, the associations among skin microbiota, circulating metabolites, and epilepsy are still not well studied. In this study, we applied univariate and two-step Mendelian randomization analysis using single nucleotide polymorphisms as instrumental variables to analyze the possible associations. Five skin microbiota (asv022, asv008, bacillales, clostridiale, and micrococcaceae) and four circulating metabolites were found to be associated with epilepsy. Our results also showed that leucine level (

Indexed as

circulating metabolic biomarkerepilepsyMendelian randomization analysisskin microbiota

Identifiers

PMID39727961
PMCPMC11726749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.