Evidence map›Paper›PMID 39727888›Full record

ArticleBiosensors2024

Portable Amperometric Biosensor Enhanced with Enzyme-Ternary Nanocomposites for Prostate Cancer Biomarker Detection.

Thenmozhi Rajarathinam, Sivaguru Jayaraman, Chang-Seok Kim, Jaewon Lee, Seung-Cheol Chang

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thenmozhi RajarathinamEngineering Research Center for Color-Modulated Extra-Sensory Perception Technology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-3597-5225
Sivaguru JayaramanDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.
Chang-Seok KimEngineering Research Center for Color-Modulated Extra-Sensory Perception Technology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-2811-8137
Jaewon LeeDepartment of Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0003-3203-2130
Seung-Cheol ChangDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.ORCID 0000-0002-2333-9424

Funding

Korea Institute for Advancement of Technology (KIAT) grant funded by the Korean Government P0022108National Research Foundation of Korea (NRF) funded by the Ministry of Education 2022R1I1A3072535the Specialization Project of Pusan National University not applicable
6 · The paper itself

Abstract

Enzyme-based portable amperometric biosensors are precise and low-cost medical devices used for rapid cancer biomarker screening. Sarcosine (Sar) is an ideal biomarker for prostate cancer (PCa). Because human serum and urine contain complex interfering substances that can directly oxidize at the electrode surface, rapid Sar screening biosensors are relatively challenging and have rarely been reported. Therefore, highly sensitive and selective amperometric biosensors that enable real-time measurements within <1.0 min are needed. To achieve this, a chitosan-polyaniline polymer nanocomposite (CS-PANI NC), a carrier for dispersing mesoporous carbon (MC), was synthesized and modified on a screen-printed carbon electrode (SPCE) to detect hydrogen peroxide (H

Indexed as

Biomarkers, TumorBiosensing TechniquesHydrogen PeroxideNanocompositesProstatic NeoplasmsSarcosine OxidaseAniline CompoundsChitosanElectrochemical TechniquesElectrodesEnzymes, ImmobilizedHumansMaleSarcosineAniline CompoundsBiomarkers, TumorChitosanEnzymes, ImmobilizedHydrogen PeroxidepolyanilineSarcosineSarcosine Oxidaseamperometric biosensorchitosan-polyanilinehuman serummesoporous carbonprostate cancersarcosineurine

Identifiers

PMID39727888
PMCPMC11675002

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.