ArticleBiosensors2024
An Unlabeled Electrochemical Immunosensor Uses Poly(thionine) and Graphene Quantum Dot-Modified Activated Marigold Flower Carbon for Early Prostate Cancer Detection.
Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Article
- Electrochemical Biosensors for Cancer Diagnosis and Prognosis Using Protein Biomarkers: Current Trends, Advances, and Clinical Translation Potential.Sensors (Basel, Switzerland) · 2026Review
- Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances.Biosensors · 2025Review
- Quantum Dot-Enabled Biosensing for Prostate Cancer Diagnostics.Nanomaterials (Basel, Switzerland) · 2025Review
- Immunosensor Enhanced with Silver Nanocrystals for On-Chip Prostate-Specific Antigen Detection.Biosensors · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The activated carbon from marigold flowers (MG) was used to make an unlabeled electrochemical immunosensor to determine prostate cancer. MG was synthesized by hydrothermal carbonization and pyrolysis. MG had a large surface area, was highly conductive, and biocompatible. MG modified with graphene quantum dots produced excellent electron transfer for grafting poly(thionine) (PTH). The amine group of PTH bonded with anti-prostate-specific antigen (Anti-PSA) via glutaraldehyde, forming a layer that improved electron transfer. The binding affinity of the immunosensor, presented as the dissociation constant (Kd), was calculated using the Langmuir isotherm model. The results showed that a lower Kd value indicated greater antibody affinity. The immunosensor exhibited two different linear ranges under optimized conditions: 0.0125 to 1.0 ng mL
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Registered trials
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