Evidence map›Paper›PMID 39727841›Full record

ArticleBiosensors2024

A Cell-Based Electrochemical Biosensor for the Detection of Infectious Hepatitis A Virus.

Dilmeet Kaur, Malak A Esseili, Ramaraja P Ramasamy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dilmeet KaurNano Electrochemistry Laboratory, College of Engineering, University of Georgia, Athens, GA 30602, USA.ORCID 0009-0006-5448-8330
Malak A EsseiliCenter for Food Safety, University of Georgia, Griffin Campus, Griffin, GA 30223, USA.ORCID 0000-0002-1024-0468
Ramaraja P RamasamyNano Electrochemistry Laboratory, College of Engineering, University of Georgia, Athens, GA 30602, USA.

Funding

Center for Food Safety, University of Georgia, U.S.A. 2023
6 · The paper itself

Abstract

Hepatitis A virus (HAV), a major cause of acute liver infections, is transmitted through the fecal-oral route and close contact with infected individuals. Current HAV standardized methods rely on the detection of virus antigen or RNA, which do not differentiate between infectious and non-infectious HAV. The objective of this study was to develop a prototype cell-based electrochemical biosensor for detection of infectious HAV. A cell culture-adapted HAV strain (HM175/18f) and its permissive cells (FRhK-4), along with gold nanoparticle-modified screen-printed electrodes, were used to develop the biosensor. Electrochemical impedance spectroscopy was used to quantify the electrical impedance signal. Nyquist plots showed successful fabrication of the cell-based biosensor. The optimum period of HAV incubation with the biosensor was 6 h. A significant linear relationship (R

Indexed as

Biosensing TechniquesHepatitis A virusAnimalsCell LineDielectric SpectroscopyElectrochemical TechniquesGoldHepatitis AHumansMetal NanoparticlesGoldcell-based biosensorsfoodborne outbreaksFRhK-4 cellsHepatitis A virusimpedance spectroscopyinfectious virusesinfectivity assayscreen-printed electrodes

Identifiers

PMID39727841
PMCPMC11726883

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.