Evidence map›Paper›PMID 39727598›Full record

ArticleGels (Basel, Switzerland)2024

Antimicrobial Zn

Svetlana Bratskaya, Andrey Boroda, Tamara Bogomaz, Yuliya Privar, Mariya Maiorova, Daniil Malyshev, Anastasiia Shindina, Anna Skatova, Roman Goncharuk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Pharmacological and Biological Efficacy of Chitosan-Based Materials.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Svetlana BratskayaInstitute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159, Prosp. 100-Letiya Vladivostoka, 690022 Vladivostok, Russia.ORCID 0000-0003-4954-0422
Andrey BorodaA.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, 17 Palchevskogo Street, 690041 Vladivostok, Russia.ORCID 0000-0003-0257-748X
Tamara BogomazSchool of Medicine and Life Sciences, Far Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, Russia.ORCID 0009-0007-8606-699X
Yuliya PrivarInstitute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159, Prosp. 100-Letiya Vladivostoka, 690022 Vladivostok, Russia.
Mariya MaiorovaA.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, 17 Palchevskogo Street, 690041 Vladivostok, Russia.
Daniil MalyshevA.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, 17 Palchevskogo Street, 690041 Vladivostok, Russia.
Anastasiia ShindinaSchool of Medicine and Life Sciences, Far Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, Russia.
Anna SkatovaInstitute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159, Prosp. 100-Letiya Vladivostoka, 690022 Vladivostok, Russia.
Roman GoncharukSchool of Medicine and Life Sciences, Far Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, Russia.

Funding

Russian Science Foundation 20-13-00399
6 · The paper itself

Abstract

The local application of broad-spectrum antibiotics via polymeric drug delivery systems is a promising alternative to their systemic administration in wound healing, prevention and treatment of infections associated with surgical implants. However, low and poorly controlled loading efficiency and 100% burst release are common problems for the materials with weak physical interaction between antibiotics and polymeric matrices. Here, we report a new multifunctional carboxymethyl chitosan (CMC) cryogel, which efficiently prevents bacterial adhesion to the surface, kills bacteria in the solution via controlled release of ciprofloxacin (CIP), and promotes fibroblast proliferation. The suggested approach is based on CIP loading to Zn

Indexed as

carboxymethyl chitosanciprofloxacincytotoxicitydrug releaseFT-IR spectroscopynon-covalent interactionszinc

Identifiers

PMID39727598
PMCPMC11675459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.