Evidence map›Paper›PMID 39727518›Full record

ArticleGels (Basel, Switzerland)2024

Development of Soft Wrinkled Micropatterns on the Surface of 3D-Printed Hydrogel-Based Scaffolds via High-Resolution Digital Light Processing.

Mauricio A Sarabia-Vallejos, Scarleth Romero De la Fuente, Nicolás A Cohn-Inostroza, Claudio A Terraza, Juan Rodríguez-Hernández, Carmen M González-Henríquez

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mauricio A Sarabia-VallejosFacultad de Ingeniería, Arquitectura y Diseño, Universidad San Sebastián, Santiago 8420524, Chile.
Scarleth Romero De la FuenteDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.ORCID 0009-0000-2609-8323
Nicolás A Cohn-InostrozaInstituto Universitario de Investigación y Desarrollo Tecnológico (IDT), Ignacio Valdivieso 2409, Santiago 8940000, Chile.
Claudio A TerrazaResearch Laboratory for Organic Polymer (RLOP), Facultad de Química y Farmacia, Pontificia Universidad Católica de Chile, Santiago 7810000, Chile.ORCID 0000-0002-6326-8771
Juan Rodríguez-HernándezPolymer Functionalization Group, Departamento de Química Macromolecular Aplicada, Instituto de Ciencia y Tecnología de Polímeros-Consejo Superior de Investigaciones Científicas (ICTP-CSIC), 28006 Madrid, Spain.
Carmen M González-HenríquezDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800003, Chile.ORCID 0000-0001-9058-5425

Funding

Agencia Nacional de Investigación y Desarrollo FONDECYT 11230427Agencia Nacional de Investigación y Desarrollo FONDECYT 1220251Agencia Nacional de Investigación y Desarrollo FONDEF ID23I10110Consejo Superior de Investigaciones Científicas PIT FAB3DConsejo Superior de Investigaciones Científicas PTI + Salud GlobalConsejo Superior de Investigaciones Científicas PTI + SUSPLASTMinisterio de Ciencia, Innovación y Universidades RTI2018-096328-B-I00Ministry of Education UTM 1999
6 · The paper itself

Abstract

The preparation of sophisticated hierarchically structured and cytocompatible hydrogel scaffolds is presented. For this purpose, a photosensitive resin was developed, printability was evaluated, and the optimal conditions for 3D printing were investigated. The design and fabrication by additive manufacturing of tailor-made porous scaffolds were combined with the formation of surface wrinkled micropatterns. This enabled the combination of micrometer-sized channels (100-200 microns) with microstructured wrinkled surfaces (1-3 μm wavelength). The internal pore structure was found to play a critical role in the mechanical properties. More precisely, the TPMS structure with a zero local curvature appears to be an excellent candidate for maintaining its mechanical resistance to compression stress, thus retaining its structural integrity upon large uniaxial deformations up to 70%. Finally, the washing conditions selected enabled us to produce noncytotoxic materials, as evidenced by experiments using AlamarBlue to follow the metabolic activity of the cells.

Indexed as

3D porous scaffoldsstereolithographywrinkled nonplanar surfaces

Identifiers

PMID39727518
PMCPMC11675352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.