Evidence map›Paper›PMID 39727498›Full record

ArticleAdvances in respiratory medicine2024

Characterization of Serum Cytokine Patterns in Frequent-Exacerbation Asthma: Implications for Phenotyping and Management.

Dao Ngoc Bang, Pham Dac The, Pham Thi Kim Nhung, Nguyen Tien Dung, Bach Quoc Tuan, Vu Minh Duong, Le Thi Dieu Hien, Ta Ba Thang

Abstract read
In one paragraph

Article in Advances in respiratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dao Ngoc BangRespiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.
Pham Dac TheAsthma Management Department, Hai Phong International General Hospital, Hai Phong 180000, Vietnam.
Pham Thi Kim NhungRespiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.ORCID 0000-0003-3589-2515
Nguyen Tien DungRespiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.
Bach Quoc TuanRespiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.
Vu Minh DuongIntensive Care Unit, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.
Le Thi Dieu HienRespiratory Department, Hai Phong University of Medicine and Pharmacy, Hai Phong 180000, Vietnam.
Ta Ba ThangRespiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 12100, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Asthma exacerbations represent significant clinical events, however, the underlying inflammatory mechanisms and cytokine profiles in patients with frequent exacerbations remain incompletely understood; (2) Methods: In this prospective, cross-sectional study of 120 stable asthma patients, we compared the serum concentrations of eight key cytokines (IL-4, IL-12, IL-13, IL-17, IFN-α, IFN-γ, TNF-α, and IL-1β) between two groups: 60 patients with frequent exacerbations (≥ 2 events per year) and 60 matched controls with few exacerbations (1 event per year); (3) Results: Patients with frequent exacerbations showed significantly higher serum concentrations of IL-4 and IL-13 (

Indexed as

AsthmaCytokinesAdultCross-Sectional StudiesFemaleHumansInterferon-gammaInterleukin-12Interleukin-13Interleukin-17Interleukin-4MaleMiddle AgedPhenotypeProspective StudiesTumor Necrosis Factor-alphaCytokinesInterferon-gammaInterleukin-12Interleukin-13Interleukin-17Interleukin-4Tumor Necrosis Factor-alphaasthma phenotypefrequent asthma exacerbationsserum cytokine

Identifiers

PMID39727498
PMCPMC11673841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.