Evidence map›Paper›PMID 39727496›Full record

ReviewAdvances in respiratory medicine2024

Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities.

Anastasia Ganina, Manarbek Askarov, Larissa Kozina, Madina Karimova, Yerzhan Shayakhmetov, Perizat Mukhamedzhanova, Aigul Brimova, Daulet Berikbol, Elmira Chuvakova, Lina Zaripova and 1 more

Abstract readReview
In one paragraph

Review in Advances in respiratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anastasia GaninaJSC National Scientific Medical Center, Astana 010009, Kazakhstan.
Manarbek AskarovJSC National Scientific Medical Center, Astana 010009, Kazakhstan.
Larissa KozinaJSC National Scientific Medical Center, Astana 010009, Kazakhstan.
Madina KarimovaJSC National Scientific Medical Center, Astana 010009, Kazakhstan.
Yerzhan ShayakhmetovInternational Oncological Tomotherapy Center "YMIT", Astana 010009, Kazakhstan.
Perizat MukhamedzhanovaInternational Oncological Tomotherapy Center "YMIT", Astana 010009, Kazakhstan.
Aigul BrimovaInternational Oncological Tomotherapy Center "YMIT", Astana 010009, Kazakhstan.
Daulet BerikbolInternational Oncological Tomotherapy Center "YMIT", Astana 010009, Kazakhstan.
Elmira ChuvakovaJSC National Scientific Medical Center, Astana 010009, Kazakhstan.
Lina ZaripovaJSC National Scientific Medical Center, Astana 010009, Kazakhstan.ORCID 0000-0001-8728-0225
Abay BaigenzhinJSC National Scientific Medical Center, Astana 010009, Kazakhstan.

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan 19680098
6 · The paper itself

Abstract

This review explores the significance and prospects of using diverse T-cell variants in the context of combined therapy for lung cancer treatment. Recently, there has been an increase in research focused on understanding the critical role of tumor-specific T lymphocytes and the potential benefits of autologous T-cell-based treatments for individuals with lung cancer. One promising approach involves intravenous administration of ex vivo-activated autologous lymphocytes to improve the immune status of patients with cancer. Investigations are also exploring the factors that influence the success of T-cell therapy and the methods used to stimulate them. Achieving a comprehensive understanding of the characteristics of activated lymphocytes and deciphering the mechanisms underlying their activation of innate anti-tumor immunity will pave the way for numerous clinical trials and the development of innovative strategies for cancer therapy like combined immunotherapy and radiation therapy.

Indexed as

Lung NeoplasmsCombined Modality TherapyHumansImmunotherapyLymphocyte ActivationT-Lymphocytesactivationimmunosuppressionimmunotherapylung cancerlymphocytestumor

Identifiers

PMID39727496
PMCPMC11673795

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.