Evidence map›Paper›PMID 39727469›Full record

ArticleDentistry journal2024

Effectiveness of Lidocaine with Epinephrine Irrigation in Reducing Acute Pain from Surgical Removal of Mesioangular-Impacted Third Molars.

Vuttinun Chatupos, Molee Apiphathanamontri, Sumatee Yuthavong, Piyanart Chatiketu, Nuntouchaporn Hutachok, Somdet Srichairatanakool

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Article in Dentistry journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Vuttinun ChatuposDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
Molee ApiphathanamontriDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
Sumatee YuthavongDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
Piyanart ChatiketuDepartment of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai 50200, Thailand.
Nuntouchaporn HutachokDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-3856-5309
Somdet SrichairatanakoolDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-5706-8781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnesthetic irrigation is an effective treatment for postoperative pain suppression in patients after molar extraction, but exerts a short period of extraction. The study aimed to evaluate the effect of lidocaine with epinephrine irrigation on acute pain relief in healthy volunteers with inferior alveolar nerve block (IANB) injection for the surgical removal of mesioangular (MA)-impacted third molars.

methodsA total of 28 patients (56 samples) with bilateral MA-impacted third molars were recruited. This study was a split-mouth, double-blind, randomized clinical trial. Surgical procedures were conducted over two separate appointments. Each patient randomly received 2% lidocaine with 1:100,000 epinephrine for the irrigation of the extraction site after surgery on one side of the mouth and normal saline solution on the other side. The postoperative visual analog scale (VAS) as a pain indicator was recorded and statistically analyzed for both treatments.

resultsThe VAS levels at 3 and 4 h after surgery in the lidocaine group were significantly lower than those of the normal saline group. Increases in pain scores were recorded five hours after surgery in both groups. No complications were recorded during this study.

conclusionsContinuous local anesthetic irrigation appears to be effective in reducing acute postoperative pain in patients with IANB for MA-impacted third molar surgery. CLINICAL TRIAL REGISTRY: Reference number ISRCTN13866362, Date: 1 October 2024.

Indexed as

anestheticlidocainenerve blockpainthird molarVAS

Identifiers

PMID39727469
PMCPMC11674364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.