ReviewDentistry journal2024
A Review of White Spot Lesions: Development and Treatment with Resin Infiltration.
Review in Dentistry journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Awareness and perception of white spot lesions amongst adolescents undergoing orthodontic treatment with fixed appliances: a cross-sectional study of caries preventive adherence.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Investigation of enamel surface changes in teeth with artificially produced white spot lesions after debonding: an in vitro study.BMC oral health · 2026Article
- Tooth Enamel Demineralization: Caries and Erosion from the Viewpoint of Chemistry.Dentistry journal · 2026Review
- Influence of White Spot Lesion Severity on the Structural, Optical, and Mechanical Outcomes of Resin Infiltration: An In Vitro Study.Diagnostics (Basel, Switzerland) · 2026Article
- In Vitro Evaluation of the Effect of Microabrasion and Resin Infiltration Materials on Enamel Microhardness and Penetration Depth.Journal of functional biomaterials · 2026Article
- The impact of clear aligners therapy on dental caries: a systematic review.Frontiers in dental medicine · 2026Review
- Prevalence of white spot lesions in children and adolescents across Northern, Central and Southern Italy: a multicenter cross-sectional study.Frontiers in oral health · 2026Article
- Resin infiltration and oral health-related quality of life in children and adolescents: a narrative review.Frontiers in dental medicine · 2026Review
- Enamel Microhardness of Resin-Infiltrated White Spot Lesions After Bleaching With and Without ACP: An In Vitro Study.International journal of dentistry · 2026Article
- Esthetic rehabilitation of traumatic enamel defects using resin infiltration and microabrasion: a two-case report.Frontiers in dental medicine · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
White spot lesions (WSLs) are demineralized lesions of the enamel that form in the presence of bacterial plaque, affecting the aesthetics by modifying the refractive index of the enamel, giving the characteristic "chalky" aspect. They have various causes, including fixed orthodontic treatments, improper hygiene, fluorosis and genetic factors. BACKGROUND/
objectivesConsidering the latest need for dental aesthetics and the popularization of fixed orthodontic treatments, the need to effectively treat WSLs has increased. The objective of this research is to review the development of WSLs and their treatment with resin infiltration.
methodsThe PubMed, Web of Science, Scopus and Google Scholar databases were searched for relevant reviews and studies. Out of all, 56 were included in this research.
resultsProphylactic measures, such as fluorized toothpaste and varnishes, have limited results. Standard caries treatment is too invasive as it removes too much healthy enamel for obturation retentivity. The resin infiltration resin process does not require drilling or tooth structure loss, making it a painless and minimally invasive treatment. The resin used has a refractive index comparable to that of healthy enamel, consequently restoring aesthetics and ensuring the prevention of caries evolvement. The treatment involves five important steps: prophylaxis, acid demineralization, alcohol drying, resin infiltration and UV light curing. Depending on the clinical case, the demineralization and drying steps may need to be repeated.
conclusionsInfiltrations with resin are painless and well tolerated by patients. Out of all minimally invasive treatments, they have an immediate satisfactory outcome, with results stable for a minimum of 45 months.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.