ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Late-life social activity and subsequent risk of dementia and mild cognitive impairment.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Social engagement, formal education, and cognitive outcomes among older adults in India: A longitudinal population-based study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Positive change in lifestyle behaviors improve cognitive health in older adults: a 10-year cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- Changes in social participation between ages 65 and 70 and incident dementia: a Bayesian competing risk analysis.BMC geriatrics · 2026Article
- Associations between self-reported change in lifestyle behaviors and brain health: Findings from the Healthy Brain Initiative.Journal of Alzheimer's disease : JAD · 2026Article
- Social determinants of health, behavioral factors, and incident dementia: a prospective cohort study.Alzheimer's research & therapy · 2026Article
- Trajectories of social health, cognitive, and daily functioning in community-dwelling older adults.Innovation in aging · 2026Article
- Association between environmental mold exposure and mild cognitive impairment in older adults: a case-control study.Frontiers in public health · 2026Article
- Is social connection the key to prevention? Educational attainment, incident dementia, and the role of later-life social engagement.Innovation in aging · 2026Article
- Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset.Frontiers in public health · 2026Article
- An updated systematic review and meta-analysis of tooth loss in patients with periodontitis and the risk of mild cognitive impairment.Frontiers in oral health · 2026Review
- Analysis of Determinants Based on the Health Belief Model: A Study Predicting Cognitive Impairment Among Community-Dwelling Older Adults in China.Journal of multidisciplinary healthcare · 2026Article
- Association Between the Jiangnan Diet and Mild Cognitive Impairment Among the Elderly.Nutrients · 2025Article
- Cognitive impairment and contexts: examining the intersections of social activity participation and neighborhood perceptions.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Risk factors and predictive model for mild cognitive impairment in elderly patients with rheumatoid arthritis.BMC rheumatology · 2025Article
- Relationship of Composite Dietary Antioxidant Index vs. Alcohol Consumption with Mild Cognitive Impairment in the Elderly.Nutrients · 2025Article
- Introducing social determinants of health to the Alzheimer's Disease Research Center network: Development and implementation in the Uniform Data Set.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Critical reflections on the impact of late-life social activity on dementia and mild cognitive impairment (MCI).Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Late-life social activity and subsequent risk of dementia and mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association between varicose veins and occurrence of dementia: A nationwide population-based cohort study.PloS one · 2025Article
- Social determinants of health, genetic biomarkers, and cognitive function in Chinese older adults with subjective cognitive decline and mild cognitive impairment: A cross-sectional analysis.Journal of Alzheimer's disease reportsArticle
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6 authors.
Funding
Abstract
introductionSocial activity is associated with better cognitive health in old age. To better translate epidemiological research for public health communication, we estimated relations of levels of social activity to average age at dementia onset.
methodsIn the Rush Memory and Aging Project (MAP), we followed 1923 dementia-free older adults and conducted annual clinical evaluations of dementia/mild cognitive impairment (MCI).
resultsDuring a mean follow-up of 6.7 (SD = 4.7) years, 545 participants developed dementia, and 695 developed MCI. Using Accelerated Failure Time models adjusted for age, sex, education, race/ethnicity, and marital status, we found predicted mean age of dementia onset for the least socially active was 87.7 years, approximately 5 years earlier than the most socially active (mean age = 92.2, p < .01); we found a similar 5-year difference in age at MCI onset by social activity. DISCUSSION: Our findings highlight the value of social activity as a possible community-level intervention for reducing dementia. HIGHLIGHTS: Accelerated failure time models estimated age at dementia onset by social activity level to aid interpretation. Higher social activity was associated with a 5-year older age at dementia onset. Economic research shows a 5-year delay translates to US$500,000 of healthcare savings per capita. Our findings help understand the public health significance of social activity.
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