Evidence map›Paper›PMID 39727055›Full record

ArticleCirculation. Cardiovascular interventions2025

Extended Rhythm Monitoring to Assess for Ventricular Arrhythmias After Transcatheter Pulmonary Valve Replacement With the Harmony Valve.

Jeffrey K Yang, Laura Wattenbarger, Anne C Taylor, Henry Chubb, Anitra W Romfh, Lynn F Peng, Scott R Ceresnak, Anne M Dubin, Doff B McElhinney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Cardiovascular interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeffrey K YangDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0003-4675-402X
Laura WattenbargerDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0003-4436-7106
Anne C TaylorDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0002-2133-4419
Henry ChubbDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0002-2859-3536
Anitra W RomfhDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0002-8547-8761
Lynn F PengDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.
Scott R CeresnakDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0002-9473-0105
Anne M DubinDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0002-3786-1408
Doff B McElhinneyDepartment of Pediatrics, Pediatric Cardiology (J.K.Y., L.W., A.C.T., H.C., A.W.R., L.F.P., S.R.C., A.M.D., D.B.M.), Stanford University, Palo Alto, CA.ORCID 0000-0001-7242-0934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarying rates of nonsustained ventricular tachycardia (NSVT) have been reported early after transcatheter pulmonary valve replacement (TPVR) with the Harmony valve, but data regarding rhythm outcomes beyond hospital discharge are limited. This study aims to characterize ventricular arrhythmias after Harmony TPVR from implant through mid-term follow-up.

methodsVentricular arrhythmia data from postimplant telemetry and follow-up extended rhythm monitoring (ERM) were analyzed after Harmony TPVR.

resultsFifty-four patients with tetralogy of Fallot (n=39), valvar pulmonary stenosis (n=10), or pulmonary atresia with intact ventricular septum (n=5) were studied; 22% had prior NSVT and 24% were on prior rhythm medication. On postimplant telemetry, 27 patients (50%) had NSVT, including 1 who had torsade de pointes, but most had <5 episodes. Pre-TPVR NSVT or rhythm medications, diagnosis other than tetralogy, and substantial device contact with the myocardium were associated with more frequent NSVT on telemetry. Ten patients (19%) were started on a new antiarrhythmic medication. On discharge ERM, 37% of patients had NSVT, most with <5 episodes and only 13% with NSVT beyond 5 days post-discharge. On follow-up ERM, 14% of patients had a single episode of NSVT and 1 had 5 episodes. During follow-up, antiarrhythmic medications were discontinued in 8 of 10 patients and no patients died or had sustained ventricular tachycardia.

conclusionsNSVT and ventricular ectopy were common early after TPVR but were infrequent in most cases and diminished rapidly after discharge. The incidence of NSVT on follow-up ERM was similar to preimplant incidence. Few patients had antiarrhythmic medications initiated, and most were discontinued on follow-up. There were no major arrhythmic events after discharge.

Indexed as

Cardiac CatheterizationElectrocardiography, AmbulatoryHeart RateHeart Valve ProsthesisHeart Valve Prosthesis ImplantationPulmonary ValveTachycardia, VentricularAdolescentAdultAnti-Arrhythmia AgentsChildChild, PreschoolFemaleHumansMaleMiddle AgedAnti-Arrhythmia Agentscardiac catheterizationheart valve prosthesis implantationpulmonary valvepulmonary valve insufficiencytachycardia, ventriculartetralogy of Fallottranscatheter pulmonary valve replacement

Identifiers

PMID39727055
PMCPMC11748900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.