Evidence map›Paper›PMID 39726986›Full record

ArticleProceedings. IEEE International Conference on Healthcare Informatics2024

Identifying Symptoms of Delirium from Clinical Narratives Using Natural Language Processing.

Aokun Chen, Daniel Paredes, Zehao Yu, Xiwei Lou, Roberta Brunson, Jamie N Thomas, Kimberly A Martinez, Robert J Lucero, Tanja Magoc, Laurence M Solberg and 6 more

Abstract read
In one paragraph

Article in Proceedings. IEEE International Conference on Healthcare Informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Aokun ChenDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Daniel ParedesDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Zehao YuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Xiwei LouDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Roberta BrunsonUF Health Shands Hospital, Gainesville, FL, USA.
Jamie N ThomasUF Health Shands Hospital, Gainesville, FL, USA.
Kimberly A MartinezUF Health Shands Hospital, Gainesville, FL, USA.
Robert J LuceroSchool of Nursing, University of California Los Angeles, Los Angeles, CA, USA.
Tanja MagocUF Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA.
Laurence M SolbergNorth Florida/South Georgia, Veterans Health Service, Geriatrics Research, Education, and Clinical Center (GRECC), Gainesville, FL, USA.
Urszula A SnigurskaCollege of Nursing, University of Florida, Gainesville, FL, USA.
Sarah E SerDepartment of Epidemiology, University of Florida, Gainesville, FL, USA.
Mattia ProsperiDepartment of Epidemiology, University of Florida, Gainesville, FL, USA.
Jiang BianDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.
Ragnhildur I BjarnadottirCollege of Nursing, University of Florida, Gainesville, FL, USA.
Yonghui WuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Computational Drug Repurposing for AD/ADRD with Integrative Analysis of Real World Data and Biomedical KnowledgeR01AG076234 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jiang Bian, Fei Wang · 2022 to 2026
$3.8M
Eligibility criteria design for Alzheimer's trials with real-world data and explainable AIR01AG080991 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jiang Bian, Fei Wang · 2023 to 2026
$3.1M
Disparities of Alzheimer's disease progression in Sexual Minority IndividualsR01AG080624 · NIA · UNIVERSITY OF FLORIDA · PI Jiang Bian, Yi Guo · 2023 to 2026
$3.1M
Advancing Interdisciplinary Science of Aging through Identification of Iatrogenic Complications: The UF EHR Clinical Data Infrastructure for Enhanced Patient Safety among the Elderly (UF-ECLIPSE)R33AG062884 · NIA · UNIVERSITY OF FLORIDA · PI INGIBJARGARDOTTIR BJARNADOTTIR, RAGNHILDUR, LUCERO, ROBERT J · 2021 to 2023
$2.1M
Advancing Drug Repositioning for Alzheimer’s Disease using Real-world DataR56AG069880 · NIA · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, CHEN, YONG · 2021 to 2022
$1.6M
NCATS NIH HHS UL1 TR001427NIA NIH HHS R01 AG076234NIA NIH HHS R01 AG080624NIA NIH HHS R01 AG080991NIA NIH HHS R33 AG062884NIA NIH HHS R56 AG069880
6 · The paper itself

Abstract

Delirium is an acute decline or fluctuation in attention, awareness, or other cognitive function that can lead to serious adverse outcomes. Despite the severe outcomes, delirium is frequently unrecognized and uncoded in patients' electronic health records (EHRs) due to its transient and diverse nature. Natural language processing (NLP), a key technology that extracts medical concepts from clinical narratives, has shown great potential in studies of delirium outcomes and symptoms. To assist in the diagnosis and phenotyping of delirium, we formed an expert panel to categorize diverse delirium symptoms, composed annotation guidelines, created a delirium corpus with diverse delirium symptoms, and developed NLP methods to extract delirium symptoms from clinical notes. We compared 5 state-of-the-art transformer models including 2 models (BERT and RoBERTa) from the general domain and 3 models (BERT_MIMIC, RoBERTa_MIMIC, and GatorTron) from the clinical domain. GatorTron achieved the best strict and lenient F1 scores of 0.8055 and 0.8759, respectively. We conducted an error analysis to identify challenges in annotating delirium symptoms and developing NLP systems. To the best of our knowledge, this is the first large language model-based delirium symptom extraction system. Our study lays the foundation for the future development of computable phenotypes and diagnosis methods for delirium.

Indexed as

clinical natural language processingdeep learningdeliriummedication information extractionnamed entity recognition

Identifiers

PMID39726986
PMCPMC11670120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.