ReviewFrontiers in microbiology2024
Endophytic fungi: nature's solution for antimicrobial resistance and sustainable agriculture.
Review in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Antimicrobial and Antibiofilm Activity of an Endophytic Fungus, Daldinia sp. Isolated From Avicennia officinalis.MicrobiologyOpen · 2026Article
- Endophytic Fungi from WildJournal of fungi (Basel, Switzerland) · 2026Article
- Chemical Constituents of the Endophytic FungusMolecules (Basel, Switzerland) · 2026Article
- Unveiling the diversity, bioactive metabolites and therapeutic potential of endophytic fungi of the Apocynaceae family: a comprehensive review.Archives of microbiology · 2026Review
- Identification and Biocontrol of Pathogenic Fungi Causing Root Rot ofJournal of fungi (Basel, Switzerland) · 2026Article
- Virulence modulation and biofilm inhibition of Streptococcus pyogenes by metabolites from endophytic fungi associated with Vanda tessellata.Molecular biology reports · 2026Article
- Characterization of an Endophytic Fusarium odoratissimum Strain 25Current microbiology · 2026Article
- Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.Microbial cell factories · 2026Review
- Rapid Discovery of Antifungal α-Pyrone Analogs fromJournal of fungi (Basel, Switzerland) · 2026Article
- Mining the Hidden Pharmacopeia: Fungal Endophytes, Natural Products, and the Rise of AI-Driven Drug Discovery.International journal of molecular sciences · 2026Review
- Discovery of penicillic acid from mangrove endophytic fungi: anti-Frontiers in microbiology · 2026Article
- Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistantMycology · 2026Review
- The endophyteFrontiers in microbiology · 2026Article
- Endophyte-mediated pest resistance: mechanisms, evidence gaps, and translational opportunities.Frontiers in microbiomes · 2026Review
- Multiomics analysis of the Silkworm cocoon shell.Scientific data · 2025Article
- Investigating the potential antibacterial, anti-biofilm, wound healing and anti-inflammatory activity of the extract of Aspergillus niger endophyte isolated from cucumber leaves: in vitro and in vivo study.BMC microbiology · 2025Article
- Anti-Inflammatory Effect of Pestalotic Acid A Derived fromBiomedicines · 2025Article
- Investigating endophytic fungi of Calotropis procera for novel bioactive compounds: molecular docking and bioactivity insights.Microbial cell factories · 2025Article
- Recent advances in Polygonaceae endophytes: diversity, secondary metabolites and biotechnological applications.Frontiers in bioengineering and biotechnology · 2025Review
- Genome mining and OSMAC strategies unveil diverse secondary metabolites from the endophytic fungusFrontiers in microbiology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing threat of antimicrobial resistance (AMR) has underlined the need for a sustained supply of novel antimicrobial agents. Endophyte microorganism that reside within plant tissues as symbionts have been the source of potential antimicrobial substances. However, many novel and potent antimicrobials are yet to be discovered from these endophytes. The present study investigates the potential of endophytic fungi as a source of novel bioactive chemicals with antibacterial capabilities. These fungi synthesize secondary metabolites such as polyketides and peptides via polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) pathways. Notable substances, like prenylated indole alkaloids and fumaric acid, have shown promising antibacterial and antifungal properties against multidrug-resistant infectious agents. This review also emphasizes the symbiotic link between endophytes and their host plants, which is critical for secondary metabolite production. The study focuses on the significance of isolation methods for endophytes and proposes their use in for sustainable agriculture, bioremediation, and medicine. Future research combining endophytic biodiversity analysis with next-generation sequencing (NGS) and nanotechnology could provide novel techniques for combating AMR and contributing to sustainability across multiple industries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.