ArticleFrontiers in cardiovascular medicine2024
The causal relationship between 233 metabolites and coronary atherosclerosis: a Mendelian randomization study.
Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed.
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Authors and funding
7 authors.
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Abstract
Objective: To investigate the causal relationship between 233 newly reported metabolites and coronary atherosclerosis through Mendelian randomization analysis. Methods: Five different methods were used to perform Mendelian randomization analysis on the 233 metabolites and coronary atherosclerosis, with inverse variance weighting as the primary result, supplemented by other methods. Results: The analysis identified that certain metabolites increase the susceptibility risk of coronary atherosclerosis, including: Total fatty acids (OR = 1.40, 95% CI: 1.28-1.53, Conclusion: There is a close relationship between metabolites and the occurrence of coronary atherosclerosis. This study conducted Mendelian randomization analysis on the causal relationship between 233 metabolites and coronary atherosclerosis, providing potential new insights for the treatment of this disease.
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