ArticleInternational journal on magnetic particle imaging2022
A sensitive, stable, continuously rotating FFL MPI system for functional imaging of the rat brain.
Article in International journal on magnetic particle imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Magnetoelectric Nanoparticle-Based Wireless Brain-Computer Interface: Underlying Physics and Projected Technology Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Enhanced performance of a single-sided MPI scanner with a hybrid surface-volume excitation coil.Physics in medicine and biology · 2025Article
- Preclinical and Clinical-Scale Magnetic Particle Imaging of Natural Killer Cells: in vitro and ex vivo Demonstration of Cellular Sensitivity, Resolution, and Quantification.Molecular imaging and biology · 2025Article
- Design, construction and validation of a magnetic particle imaging (MPI) system for human brain imaging.Physics in medicine and biology · 2025Article
- Measurement of Peripheral Nerve Magnetostimulation Thresholds of a Head Solenoid Coil Between 200 Hz and 88.1 kHz.IEEE journal of translational engineering in health and medicine · 2025Article
- Magnetic particle imaging enables nonradioactive quantitative sentinel lymph node identification: feasibility proof in murine models.Radiology advances · 2024Article
- Advances in Vascular Diagnostics using Magnetic Particle Imaging (MPI) for Blood Circulation Assessment.Advanced healthcare materials · 2024Review
- Open-source device for high sensitivity magnetic particle spectroscopy, relaxometry, and hysteresis loop tracing.The Review of scientific instruments · 2024Article
- Functional magnetic particle imaging (fMPI) of cerebrovascular changes in the rat brain during hypercapnia.Physics in medicine and biology · 2023Article
- A sensitive, stable, continuously rotating FFL MPI system for functional imaging of the rat brain.International journal on magnetic particle imaging · 2022Article
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Authors and funding
7 authors.
Funding
Abstract
Magnetic particle imaging noninvasively maps the distribution of superparamagnetic iron oxide nanoparticles with high sensitivity. Since the particles are confined to the blood pool within the brain, it may be well-suited for cerebral blood volume (CBV)-based functional neuroimaging with MPI (fMPI). Here, we present a magnetic particle imaging system designed to detect the CBV modulation at the hemodynamic timescale (~5 sec) in rodents. It has the capacity to record sufficiently fast image time-series for several hours continuously. The time-series imaging was achieved with an optimized drive coil that maintains ~0.01% per minute current magnitude stability. An electrical slip ring and rotary union for cooling water allows continuous mechanical rotation of the 2.83 T/m Field-Free Line (FFL) permanent magnets and shift coils. The system achieves a 6.7 ng Fe detection limit (SNR = 5) in a single 5 sec image in the time-series, a spatial resolution of 3.0 mm in a 3 cm diameter field of view. The designs have been made open-source to enable replication of this device.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.