Evidence map›Paper›PMID 39726826›Full record

ArticleThe American statistician2024

Proximal MCMC for Bayesian Inference of Constrained and Regularized Estimation.

Xinkai Zhou, Qiang Heng, Eric C Chi, Hua Zhou

Abstract read
In one paragraph

Article in The American statistician, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond Scores: Proximal Diffusion Models.Advances in neural information processing systems · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinkai ZhouDepartment of Biostatistics, UCLA.
Qiang HengDepartment of Computational Medicine, UCLA.
Eric C ChiDepartment of Statistics, Rice University.
Hua ZhouDepartment of Biostatistics, UCLA.

Funding

Genomics, GPUs, and Next Generation Computational StatisticsR01HG006139 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SOBEL, ERIC · 2011 to 2023
$5.1M
Modeling, Inference, and Optimization for Genomic and Biomedical Big DataR35GM141798 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LANGE, KENNETH L · 2021 to 2025
$2.7M
Imputing Single Cell Rna Sequencing Data: Mathematical, Statistical And Computational ChallengesR01GM135928 · NIGMS · RICE UNIVERSITY · PI CHI, ERIC C · 2019 to 2021
$696k
NHGRI NIH HHS R01 HG006139NIGMS NIH HHS R01 GM135928NIGMS NIH HHS R35 GM141798
6 · The paper itself

Abstract

This paper advocates proximal Markov Chain Monte Carlo (ProxMCMC) as a flexible and general Bayesian inference framework for constrained or regularized estimation. Originally introduced in the Bayesian imaging literature, ProxMCMC employs the Moreau-Yosida envelope for a smooth approximation of the total-variation regularization term, fixes variance and regularization strength parameters as constants, and uses the Langevin algorithm for the posterior sampling. We extend ProxMCMC to be fully Bayesian by providing data-adaptive estimation of all parameters including the regularization strength parameter. More powerful sampling algorithms such as Hamiltonian Monte Carlo are employed to scale ProxMCMC to high-dimensional problems. Analogous to the proximal algorithms in optimization, ProxMCMC offers a versatile and modularized procedure for conducting statistical inference on constrained and regularized problems. The power of ProxMCMC is illustrated on various statistical estimation and machine learning tasks, the inference of which is traditionally considered difficult from both frequentist and Bayesian perspectives.

Indexed as

Hamiltonian Monte CarloMoreau-Yosida envelopeProximal mapping

Identifiers

PMID39726826
PMCPMC11670895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.