Evidence map›Paper›PMID 39726825›Full record

ArticleAdvances in ophthalmology practice and research

Global incidence and prevalence in uveal melanoma.

Xincen Hou, Alexander C Rokohl, Xueting Li, Yongwei Guo, Xiaojun Ju, Wanlin Fan, Ludwig M Heindl

Abstract read
In one paragraph

Article in Advances in ophthalmology practice and research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Deep learning for early diagnosis of uveal melanoma: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Review
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  11. Article
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  15. Ocular Melanoma: A Comprehensive Review with a Focus on Molecular Biology.International journal of molecular sciences · 2025
    Review
  16. Article
  17. Management of liver metastases from uveal melanoma.The British journal of surgery · 2025
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xincen HouDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Alexander C RokohlDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Xueting LiDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Yongwei GuoEye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Xiaojun JuDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Wanlin FanDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Ludwig M HeindlDepartment of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The most common intraocular cancer in adults is uveal melanoma (UM). This study aimed to investigate and report the incidence and prognosis of UM in different regions of the world. Methods: We retrieved relevant data on UM from the PubMed database and analyzed its global incidence and prognosis. All data was obtained from a national population-based registry, with publication dates ranging from 2013 to 2023. Results: The incidence rates of UM vary across different regions: in the United States, rates were 5.1 per million (1993-2008) and 5.2 per million (1973-2013); in Canada, rates ranged from 3.34 per million (1992-2010) to 5.09 per million (2011-2017); in Republic of Korea, the rate was 0.42 per million (1999-2011); in New Zealand, it was 5.56 per million (2000-2020); in Australia, it was 7.6 per million (1982-2014); and in Europe, rates ranged from 3.1 to 5.8 per million (1995-2002). Among European countries, Sweden (5.6 per million (1960-2009)), Germany (6.41 per million (2009-2015)), Poland (6.67 per million (2010-2017)), and the United Kingdom (10 per million (1999-2010)). Conclusions: The most common site of occurrence for UM is in the choroid. Limited data suggest a stable trend in UM incidence rates across the included countries, but significant differences in incidence rates exist among different countries and regions, with notably lower rates in Asian countries compared to Europe, North America, and Oceania. In general, the incidence rate in males is slightly higher compared to that in females.

Indexed as

EpidemiologyIncidenceUveal melanoma

Identifiers

PMID39726825
PMCPMC11670701

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.